NATURE OF BONE CARBONATE
NATURE OF BONE CARBONATE
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DOI：
10.1097/00003086-197711000-00040
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发表时间：
1977-01-01
影响因子：
4.2
通讯作者：
PELLEGRINO, ED
中科院分区：
文献类型：
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作者：
BILTZ, RM;PELLEGRINO, ED
图1所示。骨矿物质组成和C03=位置的流行概念。虽然骨CO的量是可变的，但可能以[HC03-]的形式存在于溶液中，本文不打算提及这一可溶性组分。磷灰石对oh -磷灰石结构与碳酸盐有一定的调和作用，但不能真正区分oh -磷灰石与含c03的生物磷灰石。25. 此外，在水热条件下，C03=可能取代PO，或oh -在oh -磷灰石中的oh -在很大程度上是非生理性的。11.45. 在近似生理条件下，c03 '是否与oh -磷灰石结构相容是另一个问题。骨矿物是由酸性磷酸钙前体转化而成的，没有明显的x射线结构，x射线衍射分析只能勉强识别出属于磷灰石家族的细板状晶体。随着骨矿物质的成熟，CO: r=增加，PO,-(HPO,=)减少。60这些变化与钴磷灰石的形成一致。因此，联合国的干预并非不可思议
FIG. 1. Popular concepts of bone mineral composition and the location of C03=. Although variable amounts of bone CO, probably exist in solution as [HC03-] no reference to this soluble frac-tion is intended. apatites offer some reconciliation of OH-apatite structure with carbonate, but fail to make any real distinction between OH-apatite on the one hand, and the biological C03-containing apatites on the other. 25. s5 Furthermore, the hydrothermal conditions under which C03= may replace PO,'or OH-in OH-apatite are grossly nonphysiological. 11.45. 64Whether or not C03'is compatible with the OH-apatite structure at all under conditions approximating the physiological is another question. Bone mineral is formed in viw by the conversion of an acidic calcium phosphate precursor, with no apparent X-ray structure, to a fine platy crystallite which is just barely identifiable by X-ray diffraction analysis as belonging to the family of apatites. 67 As bone mineral matures, CO: r= increases as PO,-(HPO,=) decreases. 60 These changes are coincident with the formation of COR-apatite. It is not inconceivable, therefore, the CO:{= interferes