Hyperthermia: How Can It Be Used?

Hyperthermia: How Can It Be Used?
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DOI:
10.5001/omj.2016.19
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发表时间:
2016-03-01
影响因子:
--
通讯作者:
Aghdam, Reza Zohdi
Aghdam, Reza Zohdi
中科院分区:
其他
文献类型:
--
作者:
Behrouzkia, Zhaleh;Joveini, Zahra;Aghdam, Reza Zohdi

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热疗(HT)是一种通过提高细胞温度来治疗肿瘤的方法。该治疗可以与其他经过验证的癌症治疗方法结合使用几种不同的程序。我们试图提出一个不同的HT肿瘤治疗,在该领域的最新进展,以及联合治疗序列和结果的概述。我们使用计算机辅助检索来识别包含关键词热疗、癌症治疗、化疗、放疗、纳米颗粒和顺铂的文章。有三种类型的HT治疗,每种治疗都需要使用与患者接触或接近患者的施源器进行加热。加热可以使用不同类型的能量(包括微波、无线电波和超声波)来实现。然而,能量的来源将取决于癌症的类型和位置。使用的温度也会有所不同。HT很少单独使用,可以与其他癌症治疗方法联合使用。当与其他治疗组合使用时,观察到存活率提高。然而,尽管体外和体内研究支持使用同时低温治疗,矛盾的结果表明,有必要进行更多的研究,以确定其他隐藏的影响HT。
Hyperthermia (HT) is a method used to treat tumors by increasing the temperature of the cells. The treatment can be applied in combination with other verified cancer treatments using several different procedures. We sought to present an overview of the different HT tumor treatment, recent advances in the field, and combinational treatment sequences and outcomes. We used a computer-aided search to identify articles that contained the keywords hyperthermia, cancer treatment, chemotherapy, radiotherapy, nanoparticle, and cisplatin. There are three types of HT treatment, which each need the use of applicators that are in contact with or in the proximity of the patient for the purpose of heating. Heating can be achieved using different types of energy (including microwaves, radio waves, and ultrasound). However, the source of energy will depend on the cancer type and location. The temperature used will also vary. HT is rarely used alone, and can be combined with other cancer treatments. When used in combination with other treatments, improved survival rates have been observed. However, despite in vitro and in vivo studies that support the use of concurrent hypothermia treatments, contradictory results suggest there is a need for more studies to identify other hidden effects of HT.