CENTRAL HEMODYNAMIC ASSESSMENT OF NORMAL TERM PREGNANCY
CENTRAL HEMODYNAMIC ASSESSMENT OF NORMAL TERM PREGNANCY
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DOI：
10.1016/0002-9378(89)90900-9
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发表时间：
1989-12-01
影响因子：
9.8
通讯作者：
TOLLEY, D
中科院分区：
文献类型：
--
作者：
CLARK, SL;COTTON, DB;TOLLEY, D
10 名经过仔细筛选的妊娠 36 至 38 周的初产妇接受了肺动脉插管、动脉导管放置以及左侧卧位的中央血流动力学评估。产后 11 至 13 周期间，对同一患者进行了重复研究。与非妊娠状态相比，孕晚期末期全身血管阻力、肺血管阻力、胶体渗透压、胶体渗透压-肺毛细血管楔压梯度均显着下降（p < 0.05）。怀孕与所有患者的心输出量和脉搏显着增加相关（p < 0.05）。肺毛细血管楔压、中心静脉压、左心室每搏做功指数或平均动脉压没有显着变化。通常，妊娠晚期的晚期与通过左心室每搏功指数肺毛细血管楔压比评估的高动力左心室功能无关。
Ten carefully screened primiparous patients between 36 and 38 weeks'' gestation underwent pulmonary artery catheterization, arterial line placement, and central hemodynamic assessment in the left lateral recumbent position. Studies were repeated in the same patients between 11 and 13 weeks post partum. Compared with the nonpregnant state, there was a significant fall in systemic vascular resistance, pulmonary vascular resistance, colloid oncotic pressure, and colloid oncotic pressure-pulmonary capillary wedge pressure gradient by the late phase of the third trimester (p < 0.05). Pregnancy was associated with significant rise in cardiac output and pulse in all patients (p < 0.05). There was no significant change in pulmonary capillary wedge pressure, central venous pressure, left ventricular stroke work index, or mean arterial pressure. Normally the late phase of the third trimester is not associated with hyperdynamic left ventricular function as assessed by the left ventricular stroke work index pulmonary capillary wedge pressure ratio.