Current allergic asthma and rhinitis:: diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop®) -: Results from 8329 randomized adults from the SAPALDIA study
Current allergic asthma and rhinitis:: diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop®) -: Results from 8329 randomized adults from the SAPALDIA study
复制标题
DOI：
10.1111/j.1398-9995.1998.tb03937.x
复制
发表时间：
1998-06-01
期刊：
影响因子：
12.4
通讯作者：
Brandli, O
中科院分区：
文献类型：
--
作者：
Tschopp, JM;Sistek, D;Brandli, O
总血清 IgE、Phadiatop(R) 和皮肤点刺试验 (SPT) 常用于诊断特应性疾病。然而，还没有进行过大型研究来测试它们的诊断效率。我们在瑞士人口登记处的 8329 名随机成年人中研究了这三种特应性标记物的诊断价值。当前过敏性哮喘 (CAA) 的患病率为 1.8%，当前过敏性鼻炎 (CAR) 的患病率为 16.3%。 Phadiatop 阳性、SPT 阳性（风团直径为 13 mm 的常见空气过敏原的 SPT 至少有八分之一）和总 IgE 阳性（IgE 大于或等于 100 kU/1）的患病率分别为 29%、23% 和 23%。 Phadiatop 诊断 CAA 和 CAR 的敏感性显着高于 SPT（分别为 72.5% vs 65.4%、77.1% vs 68.4%；P
Total serum IgE, Phadiatop(R), and the skin prick test (SPT) are commonly used to diagnose atopic diseases. However, no large study has ever been done to test their diagnostic efficiency. We studied the diagnostic value of these three atopic markers in 8329 well-randomized adults from the Swiss Population Registry. The prevalence of current allergic asthma (CAA) was 1.8% and of current allergic rhinitis (CAR) 16.3%. The prevalences of positive Phadiatop, positive SPT (at least, one out of eight SPT to common aeroallergens with a wheal of 13 mm), and positive total IgE (IgE greater than or equal to 100 kU/1) were 29, 23, and 23%, respectively. To diagnose CAA and CAR, the sensitivity of Phadiatop was significantly higher than that of SPT (72.5% vs 65.4%, 77.1% vs 68.4% respectively; P