Chronicity in schizophrenia: fact, partial fact, or artifact?
Chronicity in schizophrenia: fact, partial fact, or artifact?
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精神分裂症的慢性性：事实、部分事实还是人为因素？
DOI：
10.1176/ps.38.5.477
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Strauss,JS
中科院分区：
文献类型：
--
作者：
Harding,CM;Zubin,J;Strauss,JS
临床经验似乎支持这样一种观点，即精神分裂症反复发作的人可能会有一个慢性过程，在工作、社会关系和自我照顾等方面存在残留症状和持久缺陷。然而，作者对最近的长期随访研究和早期研究人员的临床经验的回顾强烈挑战了这种普遍的期望。这份报告表明，精神分裂症的长期结局存在相当大的异质性，边缘或恶化状态更多的是例外而不是规则。造成慢性病误解的因素包括过去和现在的有偏见的抽样，以及影响患者结局的众多环境和心理社会因素。
Clinical experience has appeared to support the view that persons with repeated episodes of schizophrenia can expect to have a chronic course with residual symptoms and lasting deficits in such areas as work, social relations, and self-care. However, the authors' review of recent long-term follow-up studies and of the clinical experiences of early researchers strongly challenges this pervasive expectation. This report suggests that there is considerable heterogeneity in the long-term outcome of schizophrenia, with marginal or deteriorated states more the exception than the rule. Among the contributors to the misperception of chronicity are biased sampling, both past and present, as well as a multitude of environmental and psychosocial factors that affect patient outcome.