Improving medication adherence in diabetes type 2 patients through Real Time Medication Monitoring: a Randomised Controlled Trial to evaluate the effect of monitoring patients' medication use combined with short message service (SMS) reminders
Improving medication adherence in diabetes type 2 patients through Real Time Medication Monitoring: a Randomised Controlled Trial to evaluate the effect of monitoring patients' medication use combined with short message service (SMS) reminders
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通过实时用药监测提高 2 型糖尿病患者的用药依从性：一项随机对照试验，旨在评估监测患者用药情况与短信服务 (SMS) 提醒相结合的效果
DOI：
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发表时间：
2011
影响因子：
2.8
通讯作者：
D. D. de Bakker
中科院分区：
文献类型：
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作者：
M. Vervloet;L. van Dijk;J. Santen;B. van Vlijmen;M. Bouvy;D. D. de Bakker
背景需要创新的方法来支持患者坚持药物治疗。真实的实时药物监测（RTMM）系统可对患者的药物使用情况进行真实的实时监测，并在患者忘记服药时提供短信服务（SMS）提醒。这种监控和定制提醒的组合提供了提高依从性的机会。本文介绍了干预研究的设计，旨在评估RTMM对坚持口服antidiabetes.Methods的效果/DesignRandomised对照试验（RCT），两个干预组和一个对照组，涉及2型糖尿病患者的次优水平的坚持口服antidiabetes（低于80%的基础上，药房再填充数据）。第一个干预组的患者使用RTMM，包括短信提醒和个人网页，他们可以在那里监测他们的药物使用。第二干预组的患者使用RTMM，而不使用短信提醒或网页访问。对照组的患者不接受任何干预。患者被随机分配到三个组中的一个。干预为期六个月。从干预开始前11个月至干预开始后11个月，所有患者的药房再填充数据均可用。主要结局指标是口服降糖药的依从性，根据以下数据计算：1）RTMM收集的数据，作为按处方服用药物的百分比，以及在正确时间间隔内服用药物的百分比，2）补充数据，取研究期间分发口服降糖药的天数除以研究期间的总天数。使用再填充数据研究干预组和对照组之间的依从性差异。使用RTMM data.DiscussionThe在这篇文章中描述的干预措施包括提供RTMM次优的遵守水平的患者之间的差异进行了研究。该系统将药物使用的真实的时间监测与如果药物被遗忘的SMS提醒相结合。如果RTMM被证明是有效的，它可以被考虑用于各种患者人群，以支持患者的药物使用，并提高他们的依从性。
BackgroundInnovative approaches are needed to support patients' adherence to drug therapy. The Real Time Medication Monitoring (RTMM) system offers real time monitoring of patients' medication use combined with short message service (SMS) reminders if patients forget to take their medication. This combination of monitoring and tailored reminders provides opportunities to improve adherence. This article describes the design of an intervention study aimed at evaluating the effect of RTMM on adherence to oral antidiabetics.Methods/DesignRandomised Controlled Trial (RCT) with two intervention arms and one control arm involving diabetes type 2 patients with suboptimal levels of adherence to oral antidiabetics (less than 80% based on pharmacy refill data). Patients in the first intervention arm use RTMM including SMS reminders and a personal webpage where they can monitor their medication use. Patients in the second intervention arm use RTMM without SMS reminders or webpage access. Patients in the control arm are not exposed to any intervention. Patients are randomly assigned to one of the three arms. The intervention lasts for six months. Pharmacy refill data of all patients are available from 11 months before, until 11 months after the start of the intervention. Primary outcome measure is adherence to oral antidiabetics calculated from: 1) data collected with RTMM, as a percentage of medication taken as prescribed, and as percentage of medication taken within the correct time interval, 2) refill data, taking the number of days for which oral antidiabetics are dispensed during the study period divided by the total number of days of the study period. Differences in adherence between the intervention groups and control group are studied using refill data. Differences in adherence between the two intervention groups are studied using RTMM data.DiscussionThe intervention described in this article consists of providing RTMM to patients with suboptimal adherence levels. This system combines real time monitoring of medication use with SMS reminders if medication is forgotten. If RTMM proves to be effective, it can be considered for use in various patient populations to support patients with their medication use and improve their adherence.Trial registrationNetherlands Trial Register NTR1882
使用药物事件监测系统来评估精神分裂症患者的药物依从性。
DOI：
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发表时间：
2001
期刊：
Journal of psychiatry & neuroscience : JPN
影响因子：
--
作者：
Diaz,E;Levine,HB;Sullivan,MC;Sernyak,MJ;Hawkins,KA;Cramer,JA;Woods,SW
通讯作者：
Woods,SW