Global trends in oral and pharyngeal cancer incidence and mortality
Global trends in oral and pharyngeal cancer incidence and mortality
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DOI：
10.1002/ijc.32871
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发表时间：
2020-01-30
影响因子：
6.4
通讯作者：
La Vecchia, Carlo
中科院分区：
文献类型：
--
作者：
Bosetti, Cristina;Carioli, Greta;La Vecchia, Carlo
为了提供口腔和咽癌死亡率最新趋势的最新概述，我们分析了世界卫生组织在2010-2015年提供的全球61个国家的死亡证明数据，以及1970-2016年期间选定的人口最多的国家的死亡证明数据。对于12个最大的国家，我们分析了1960-2012年五大洲癌症发病率中所有口腔癌和咽癌的发病率及其亚位点。2015年，欧洲联盟（欧盟）的男性年龄标准化（世界人口）死亡率为每10万人5.03，俄罗斯联邦为8.33，美国（美国）为2.53，日本为3.04；女性的相应比率分别为1.23、1.23、0.82和0.76。过去几十年来，几个欧洲国家的男性死亡率有所下降，南欧下降得更早、更剧烈；相反，一些东欧国家和联合王国的死亡率仍在上升。阿根廷、澳大利亚和香港的男性死亡率也有所下降，而巴西、日本、墨西哥、韩国以及澳大利亚和美国的男性死亡率在最近的历年里趋于平稳。欧洲各国的女性死亡率略有上升。最大国家的总体发病率趋势与死亡率趋势大体一致，但口咽癌发病率在许多国家有所上升。在过去的几十年里，男性烟草和酒精暴露的变化可能解释了在世界上某些国家观察到的口腔癌和咽癌死亡率和发病率的有利趋势，而人乳头瘤病毒感染的增加可能是口咽癌发病率上升的原因。
To provide an up-to-date overview of recent trends in mortality from oral and pharyngeal cancer, we analyzed death certification data for 61 countries worldwide provided by the World Health Organization in 2010-2015, and, for selected most populous countries, over the period 1970-2016. For 12 largest countries, we analyzed incidence derived from Cancer Incidence in Five Continents in 1960-2012 for all oral and pharyngeal cancers and by subsites. In 2015, male age-standardized (world population) death rates per 100,000 were 5.03 in the European Union (EU), 8.33 in the Russian Federation, 2.53 in the United States (USA), and 3.04 in Japan; corresponding rates in women were 1.23, 1.23, 0.82, and 0.76. Male mortality decreased over the last decades in several European countries, with earlier and sharper declines in southern Europe; conversely, mortality was still increasing in a few eastern European countries and the United Kingdom. Mortality in men also decreased in Argentina, Australia, and Hong Kong, while it leveled off over more recent calendar years in Brazil, Japan, Mexico, the Republic of Korea, as well as in Australia and the USA. Female mortality slightly rose in various European countries. Overall incidence trends in the largest countries were broadly consistent with mortality ones, but oropharyngeal cancer incidence rose in many countries. Changes in tobacco and alcohol exposure in men over the last decades likely explain the favorable trends in oral and pharyngeal cancer mortality and incidence observed in selected countries worldwide, while increased human papillomavirus infection is likely responsible for the rise in oropharyngeal cancer incidence.