Breast cancer survival of American Indian/Alaska native women, 1973-1996
Breast cancer survival of American Indian/Alaska native women, 1973-1996
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DOI：
10.1007/s00038-004-4020-6
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发表时间：
2005-01-01
期刊：
影响因子：
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通讯作者：
Heeren, TC
中科院分区：
文献类型：
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作者：
Wampler, NS;Lash, TL;Heeren, TC
目的：评估美国印第安人/阿拉斯加土著妇女与非西班牙裔白色妇女在确诊后5年内的乳腺癌死亡率。方法：1973-1996年的监测、流行病学和最终结果数据用于比较两个种族的生存率，控制年龄、婚姻状况、分期和治疗。美国印第安人/阿拉斯加土著妇女的校正相对死亡风险比非西班牙裔白色妇女高58%（HR = 1.58，95% CI 1.26-2.00）。即使仅限于接受确定性治疗的女性，即乳房切除术伴腋窝淋巴结清扫或保乳手术伴腋窝淋巴结清扫和放射治疗，生存差异也持续存在（HR = 1.88，95% CI 1.40-2.52）。美洲印第安人/阿拉斯加土著妇女患乳腺癌的死亡率高于非西班牙裔白色妇女，即使仅限于接受明确乳腺癌治疗的女性。
Objective: To assess breast cancer mortality rates among American Indian/Alaska Native women compared with non-Hispanic White women in the five years after diagnosis.Methods: Surveillance, Epidemiology, and End Results data from 1973-1996 were used to compare survival in the two races, controlling for age, marital status, stage, and therapy.Results: The adjusted relative hazard of death was 58 % higher for American Indian/Alaska Native women than for non-Hispanic White women (HR = 1.58, 95 % CI 1.26-2.00). The survival disparity persisted even when limited to women who received definitive therapy, i.e. mastectomy with axillary node dissection or breast-conserving surgery with axillary node dissection and radiation treatment (HR = 1.88, 95 % CI 1.40-2.52).Conclusions: American Indian/Alaska Native women were at greater risk for breast cancer mortality than non-Hispanic White women, even when restricted to women who received definitive breast cancer therapy.