Body Mass Index, Physical Activity, and Health-Related Quality of Life in Cancer Survivors
Body Mass Index, Physical Activity, and Health-Related Quality of Life in Cancer Survivors
复制标题
DOI：
10.1249/mss.0b013e3181bdc685
复制
发表时间：
2010-04-01
期刊：
影响因子：
--
通讯作者：
Courneya, Kerry S.
中科院分区：
文献类型：
--
作者：
Blanchard, Chris M.;Stein, Kevin;Courneya, Kerry S.
BLANCHARD、C.M.、K.STEIN 和 K.S.COURNEYA。癌症幸存者的体重指数、体力活动和健康相关的生活质量。医学。科学。体育锻炼，卷。 42，第 4 期，第 665-671 页，2010 年。目的：确定乳腺癌、前列腺癌、结直肠癌、膀胱癌、子宫癌和皮肤黑色素瘤癌症幸存者的体重指数 (BMI)、体力活动 (PA) 和健康相关生活质量 (HRQoL) 之间的独立和交互关联。方法：共有 3241 名癌症幸存者完成了一项全国横断面调查，其中包括 PA 问题和 RAND-36 健康状况调查表。结果：与健康体重的幸存者相比，肥胖的乳腺癌、前列腺癌、膀胱癌和皮肤黑色素瘤幸存者达到 PA 指南的可能性明显较低。此外，健康体重和/或超重的乳腺癌、前列腺癌、结直肠癌、子宫癌和皮肤黑色素瘤幸存者与肥胖幸存者相比，身体机能明显更好，而超重结直肠癌幸存者与肥胖幸存者相比，心理健康状况明显更好。最后，分层线性回归表明，BMI x PA 交互作用对于各种癌症类型的身体或心理成分综合评分均不显着。结论：乳腺癌、前列腺癌、膀胱癌和皮肤黑色素瘤癌症幸存者中，符合美国癌症协会 PA 指南的癌症幸存者百分比似乎因体重状况而异。此外，BMI和PA与HRQoL具有独立的关联；然而，BMI 和 PA 对 HRQoL 的交互关联可以忽略不计。阐明不同癌症类型中 BMI 和 PA 之间的关系将有助于确定未来 PA 干预措施的潜在目标群体，从而有助于减轻癌症的负面副作用并提高 HRQoL。
BLANCHARD, C. M., K. STEIN, and K. S. COURNEYA. Body Mass Index, Physical Activity, and Health-Related Quality of Life in Cancer Survivors. Med. Sci. Sports Exerc., Vol. 42, No. 4, pp. 665-671, 2010. Purpose: To determine the independent and interactive associations among body mass index (BMI), physical activity (PA), and health-related quality of life (HRQoL) in breast, prostate, colorectal, bladder, uterine, and skin melanoma cancer survivors. Methods: A total of 3241 cancer survivors completed a national cross-sectional survey that included PA questions and the RAND-36 Health Status Inventory. Results: Compared with healthy-weight survivors, obese breast, prostate, bladder, and skin melanoma cancer survivors were significantly less likely to meet the PA guideline. Furthermore, healthy-weight and/or overweight breast, prostate, colorectal, uterine cancer, and skin melanoma survivors reported significantly better physical functioning compared with their obese counterparts, whereas overweight colorectal cancer survivors reported significantly better mental health compared with obese survivors. Finally, hierarchical linear regressions showed that none of the BMI x PA interactions was significant for the physical or mental component composite scores across the cancer types. Conclusions: The percentage of cancer survivors meeting the American Cancer Society's PA guideline seems to vary by weight status in breast, prostate, bladder, and skin melanoma cancer survivors. In addition, BMI and PA have independent associations with HRQoL; however, the interactive association of BMI and PA on HRQoL was negligible. Clarifying the relationship between BMI and PA across different cancer types will help identify potential target groups for future PA interventions that will help ameliorate the negative side effects of cancer and improve HRQoL.