Feasibility and acceptance of oral human papillomavirus detection in the dental office Results from The National Dental Practice-Based Research Network
Feasibility and acceptance of oral human papillomavirus detection in the dental office Results from The National Dental Practice-Based Research Network
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DOI：
10.1016/j.adaj.2018.10.022
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发表时间：
2019-02-01
影响因子：
3.9
通讯作者：
Gillison, Maura
中科院分区：
文献类型：
--
作者：
Rindal, D. Brad;Gilbert, Gregg;Gillison, Maura
背景口腔人乳头瘤病毒（HPV）感染是口咽癌急剧增加的主要潜在原因。牙科可以发挥重要作用，在制定临床算法的二级预防。作者进行了这项横断面试点研究与实践的国家牙科实践为基础的研究网络。作者评价了由从业者和患者判断的筛查和检测程序的可行性和可接受性。作者使用平板设备进行患者筛查，获得同意，并进行保密的口腔HPV危险因素调查。大多数患者（85%）对被问及吸烟和性行为（69%）感到满意，并有兴趣再次参与（79%）。超过90%的医生对研究程序感到满意，但患者参与所需的额外时间除外（75%感到满意）。患者或口腔护理人员报告的口腔冲洗液收集没有问题。这是可行的，在社区牙科诊所收集口腔冲洗液HPV检测，并要求患者明确的问题，性史时，使用平板设备的保密性。讨论高危类型的HPV并适当评估风险是口腔保健专业人员面临的挑战。从研究的角度来看，这些结果是积极的，但并没有解决牙科常规HPV筛查的可行性。
Background. Oral human papillomavirus (HPV) infection is the principal underlying cause of a dramatic increase in oropharyngeal cancer. Dentistry can play an important role in developing clinical algorithms for secondary prevention.Methods. The authors conducted this cross-sectional pilot study with practices of The National Dental Practice-Based Research Network. The authors evaluated the feasibility and acceptability of screening and testing procedures as judged by practitioners and patients. The authors used tablet devices for patient screening, obtaining consent, and administering a confidential oral HPV risk factor survey.Results. Most patients (85%) were comfortable being asked about their cigarette use and their sexual behavior (69%) and were interested in participating again (79%). More than 90% of practitioners were comfortable with study procedures except the extra time required for patient participation (75% comfortable). There were no problems with oral rinse collection as reported by patients or practitioners.Conclusions. It is feasible in community dental offices to collect oral rinses for HPV detection and to ask patients explicit questions about sexual history when using a tablet device for confidentiality.Practical Implications. Discussing high-risk types of HPV and appropriately assessing that risk are a challenge for oral health care professionals. These results are positive from a research perspective but do not address the advisability of routine HPV screening in dentistry.