Diabetes in Hispanic American Youth Prevalence, incidence, demographics, and clinical characteristics: the SEARCH for Diabetes in Youth Study
Diabetes in Hispanic American Youth Prevalence, incidence, demographics, and clinical characteristics: the SEARCH for Diabetes in Youth Study
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DOI：
10.2337/dc09-s204
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发表时间：
2009-03-01
期刊：
影响因子：
16.2
通讯作者：
Hamman, Richard F.
中科院分区：
文献类型：
--
作者：
Lawrence, Jean M.;Mayer-Davis, Elizabeth J.;Hamman, Richard F.
目的：报告2001年西班牙裔美国青少年I型和2型糖尿病的患病率和2002-2005年的发病率，并描述这些青少年的人口统计学、临床和行为特征。研究设计和方法：研究数据来自青年糖尿病研究，这是一项基于人群的多中心观察性研究，研究对象为0-19岁的医生诊断为糖尿病的青年，用于估计I型和2型糖尿病的患病率和发病率。通过问卷调查、身体检查、血液和尿液收集获得的信息进行分析，以描述完成研究访问的青年的特征。结果：在西班牙裔美国青年中，为1型。糖尿病比2型糖尿病更普遍，包括10-19岁的青少年。1型和2型糖尿病患病率没有显著的性别差异。10 ~ 14岁女性2型糖尿病发病率是男性的2倍（P < 0.005）， 15 ~ 19岁青年2型糖尿病发病率超过女性1型（P < 0.05），而男性没有。血糖控制不良（定义为A1C >= 9.5%）以及高LDL胆固醇和甘油三酯在>= 15岁的青年糖尿病患者中都很常见。44%的青少年I型糖尿病患者超重或肥胖。结论：血糖控制不良、血脂升高、超重和肥胖高发等因素可能使西班牙裔1型和2型糖尿病青年面临未来糖尿病相关并发症的风险。中国糖尿病杂志（增刊2）：123- 132,2009
OBJECTIVE - To report the 2001 prevalence and 2002-2005 incidence of type I and type 2 diabetes in Hispanic American youth and to describe the demographic, clinical, and behavioral characteristics of these Youth.RESEARCH DESIGN AND METHODS - Data from the SEARCH for Diabetes in Youth Study,a population-based multicenter observational study of youth aged 0-19 years with physician-diagnosed diabetes, were used to estimate the prevalence and incidence of type I and type 2 diabetes. Information obtained by questionnaire, physical examination, and blood and urine collection was analyzed to describe the characteristics of youth who completed a Study visit.RESULTS - Among Hispanic American youth, type 1. diabetes was more prevalent than type 2 diabetes, including in youth aged 10-19 years. There were no significant sex differences in type I or type 2 diabetes prevalence. The incidence of type 2 diabetes for female subjects aged 10-14 years was twice that of male subjects (P < 0.005), while among youth aged 15-19 years the incidence of type 2 diabetes exceeded that of type I diabetes for female subjects (P < 0,05) but not for male subjects. Poor glycemic control, defined as A1C >= 9.5%, as well as high LDL cholesterol and triglycerides were common among youth aged >= 15 years with either type of diabetes. Forty-four percent of youth With type I diabetes were overweight or obese.CONCLUSIONS - Factors such as poor glycemic control, elevated lipids, and a high prevalence of overweight and obesity may put Hispanic youth with type I and type 2 diabetes at risk for future diabetes-related complications. Diabetes Care 32 (Suppl. 2):S123-S132, 2009