Combining 3D printing and liquid handling to produce user-friendly reactionware for chemical synthesis and purification
Combining 3D printing and liquid handling to produce user-friendly reactionware for chemical synthesis and purification
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DOI：
10.1039/c3sc51253c
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发表时间：
2013-01-01
期刊：
影响因子：
8.4
通讯作者：
Cronin, Leroy
中科院分区：
文献类型：
--
作者：
Kitson, Philip J.;Symes, Mark D.;Cronin, Leroy
我们使用两个3D打印平台作为固体和液体处理制造者，通过将试剂、催化剂和纯化设备集成到单片设备中，生产用于化学合成的密封反应件。使用该反应器皿，只需旋转设备即可执行多步骤反应序列，使反应混合物在重力作用下流经连续的环境，无需任何泵或液体处理，即可从反应器皿中以纯形式回收产品。
We use two 3D-printing platforms as solid- and liquid-handling fabricators, producing sealed reactionware for chemical synthesis with the reagents, catalysts and purification apparatus integrated into monolithic devices. Using this reactionware, a multi-step reaction sequence was performed by simply rotating the device so that the reaction mixture flowed through successive environments under gravity, without the need for any pumps or liquid-handling prior to product retrieval from the reactionware in a pure form.