Interactions between leptin and insulin resistance in patients with prediabetes, with and without NAFLD
Interactions between leptin and insulin resistance in patients with prediabetes, with and without NAFLD
复制标题
DOI：
10.3892/etm.2020.9327
复制
发表时间：
2020-12-01
影响因子：
2.7
通讯作者：
Vesa, Cosmin Mihai
中科院分区：
文献类型：
--
作者：
Bungau, Simona;Behl, Tapan;Vesa, Cosmin Mihai
This study explored the link between insulin sensitivity, insulin resistance and leptinaemia in people with prediabetes with and without non-alcoholic fatty liver disease (NAFLD). A total of 143 prediabetes patients were evaluated in the study. Ultrasonography was used for diagnosis of NAFLD, and fasting insulin, postprandial insulin, leptin levels, common clinical/biochemical determinations were determined. In total, 69 (48.25%) of the patients were diagnosed with NAFLD and 74 (51.75%) without NAFLD. Leptin values correlated statistically with fasting insulin in prediabetes patients, while in the patients that were also diagnosed with NAFLD the correlation was stronger. Values of log-leptin
