Machine Independence of Ultrasound-Based Quantification of Vitreous Echodensities.
Machine Independence of Ultrasound-Based Quantification of Vitreous Echodensities.
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DOI：
10.1167/tvst.12.9.21
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发表时间：
2023-09-01
影响因子：
3
通讯作者：
Ketterling, Jeffrey A.
中科院分区：
文献类型：
--
作者：
Hoerig, Cameron;Nguyen, Justin H.;Mamou, Jonathan;Venuat, Cedric;Sebag, J.;Ketterling, Jeffrey A.
定量超声(QUS)提供与对比敏感度(CS)相关的视觉降解性肌松视(VDM)的客观指标。到目前为止，QUS方法只在一台超声仪上进行了测试。在这里，我们评估QUS测量是否与机器无关。在这项横断面研究中，对47只眼(24名受试者，年龄=53.2±14.4岁)进行了Freiburg视力对比试验(%Weber)和超声检查，两台机器：一台使用15 MHz单元件换能器，另一台使用5环20 MHz环形阵列。图像以顺序扫描的方式从每个系统获取。对无伪影的对数压缩包络数据进行处理，以产生三个参数(平均幅度M；能量E；回声密度填充百分比P50)和综合得分(C)。将B模式归一化方法应用于20-MHz数据集，以匹配两个频率下的QUS参数。进行统计分析以评估两台机器的CS、E、M、P50和C之间的相关性。每台机器的QUS参数与CS相关(R≥0.57，P<；0.001)，机器之间存在相关性(R≥0.84，P<；0.001)。除20-≥数据归一化(P=0.04)外，两台机器的CS和QUS参数之间的相关性在统计学上相似(P<0.05)。根据20兆赫数据计算的QUS参数的重复性令人满意(52.3%-96.3%)，组内相关值超过0.8(P<；0.001)。两台机器的QUS参数之间的高度相关性，再加上与CS的统计相关性，表明QUS是一种有效的、不依赖于机器的玻璃体回声密度的定量测量方法。QUS可应用于临床眼科超声扫描仪和成像频率，以有效地评估VDM。
Quantitative ultrasound (QUS) provides objective indices of Vision Degrading Myodesopsia (VDM) that correlate with contrast sensitivity (CS). To date, QUS methods were only tested on a single ultrasound machine. Here, we evaluate whether QUS measurements are machine independent. In this cross-sectional study, 47 eyes (24 subjects; age = 53.2 ± 14.4 years) were evaluated with Freiburg acuity contrast testing (%Weber), and ultrasonography using 2 machines: one with a 15-MHz single-element transducer and one with a 5-ring, 20-MHz annular-array. Images were acquired from each system in sequential scans. Artifact-free, log-compressed envelope data were processed to yield three parameters (mean amplitude, M; energy, E; and percentage filled by echodensities, P50) and a composite score (C). A B-mode normalization method was applied to the 20-MHz datasets to match QUS parameters at both frequencies. Statistical analyses were performed to evaluate correlations among CS, E, M, P50, and C for both machines. QUS parameters from each machine correlated with CS (R ≥ 0.57, P < 0.001) and there was correlation between machines (R ≥ 0.84, P < 0.001). Correlations between CS and QUS parameters were statistically similar for both machines (P ≥ 0.14) except when the 20-MHz data were normalized (P = 0.04). Reproducibility of QUS parameters computed from 20-MHz data were satisfactory (52.3%–96.3%) with intraclass correlation values exceeding 0.80 (P < 0.001). The high correlation between QUS parameters from both machines combined with a statistically similar correlation to CS suggests QUS is an effective, machine-independent, quantitative measure of vitreous echodensities. QUS may be applied across clinical ophthalmic ultrasound scanners and imaging frequencies to effectively evaluate VDM.
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DOI：
10.1097/iae.0000000000003781
发表时间：
2023-07-01
影响因子：
3.3
作者：
Boneva, Stefaniya K.;Nguyen, Justin H.;Sebag, J.
通讯作者：
Sebag, J.
影响因子：
1.4
作者：
Dennis, RJ;Beer, JMA;Thompson, WT
通讯作者：
Thompson, WT
DOI：
10.1097/iae.0000000000000065
发表时间：
2014-06-01
影响因子：
3.3
作者：
Sebag, Jerry;Yee, Kenneth M. P.;Sadun, Alfredo A.
通讯作者：
Sadun, Alfredo A.
影响因子：
1.4
作者：
Buhren, Jens;Terzi, Evdoxia;Kohnen, Thomas
通讯作者：
Kohnen, Thomas
影响因子：
2.4
作者：
INSANA, MF;WAGNER, RF;HALL, TJ
通讯作者：
HALL, TJ