Quantitative photoacoustic tomography from boundary pressure measurements: noniterative recovery of optical absorption coefficient from the reconstructed absorbed energy map
Quantitative photoacoustic tomography from boundary pressure measurements: noniterative recovery of optical absorption coefficient from the reconstructed absorbed energy map
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DOI：
10.1364/josaa.25.002347
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发表时间：
2008-09-01
影响因子：
1.9
通讯作者：
Roy, Debasish
中科院分区：
文献类型：
--
作者：
Banerjee, Biswanath;Bagchi, Srijeeta;Roy, Debasish
本文描述了一种利用模拟和噪声边界压力测量重建的吸收能量图恢复光学吸收系数分布的非迭代方法。首先解决了成像平面侧面单光源和多光源照明所对应的吸收能量图的源重建问题。结果表明，在光子通量分布变化较大的单源照明下，恢复的吸收能量图和吸收系数分布具有与重建参数相当的信噪比；L多源照明对应的光子密度分布更均匀；在控制光子输运的时间无关扩散方程（DE）中，以吸收系数乘以光子通量的形式输入吸收能量图，以单步恢复光子通量。利用回收的光子通量计算吸收能量图的光吸收系数分布。在没有实验数据的情况下，我们通过蒙特卡罗模拟获得了边界测量值，并试图解决DE模型在整体重建过程中可能存在的局限性。(C) 2008美国光学学会。
We describe a noniterative method for recovering optical absorption coefficient distribution from the absorbed energy map reconstructed using simulated and noisy boundary pressure measurements. The source reconstruction problem is first solved for the absorbed energy map corresponding to single- and multiple-source illuminations from the side of the imaging plane. It is shown that the absorbed energy map and the absorption coefficient distribution, recovered from the single-source illumination with a large variation in photon flux distribution, have signal-to-noise ratios comparable to those of the reconstructed parameters from;l more uniform photon density distribution corresponding to multiple-source illumination;. The absorbed energy map is input as absorption coefficient times photon flux in the time-independent diffusion equation (DE) governing photon transport to recover the photon flux in a single step. The recovered photon flux is used to compute the optical absorption coefficient distribution from the absorbed energy map. In the absence of experimental data, we obtain the boundary measurements through Monte Carlo simulations, and we attempt to address the possible limitations of the DE model in the overall reconstruction procedure. (C) 2008 Optical Society of America.