Seizures, cysticercosis and rural-to-urban migration: the PERU MIGRANT study

Seizures, cysticercosis and rural-to-urban migration: the PERU MIGRANT study
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DOI:
10.1111/tmi.12456
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发表时间:
2015-04-01
影响因子:
3.3
通讯作者:
Garcia, Hector H.
Garcia, Hector H.
中科院分区:
医学4区
文献类型:
--
作者:
Gonzales, Isidro;Jaime Miranda, J.;Garcia, Hector H.

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ObjectivesTo examine the prevalence of seizures, epilepsy and seropositivity to cysticercosis in rural villagers (cysticercosis-endemic setting), rural-to-urban migrants into a non-endemic urban shanty town and urban inhabitants of the same non-endemic shanty town.MethodsThree Peruvian populations (n=985) originally recruited into a study about chronic diseases and migration were studied. These groups included rural inhabitants from an endemic region (n=200), long-term rural-to-urban migrants (n=589) and individuals living in the same urban setting (n=196). Seizure disorders were detected by a survey, and a neurologist examined positive respondents. Serum samples from 981/985 individuals were processed for cysticercosis antibodies on immunoblot.ResultsEpilepsy prevalence (per 1000 people) was 15.3 in the urban group, 35.6 in migrants and 25 in rural inhabitants. A gradient in cysticercosis antibody seroprevalence was observed: urban 2%, migrant 13.5% and rural group 18% (P