Nanoscale Fe2O3-Based Catalysts for Selective Hydrogenation of Nitroarenes to Anilines
Nanoscale Fe2O3-Based Catalysts for Selective Hydrogenation of Nitroarenes to Anilines
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DOI：
10.1126/science.1242005
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发表时间：
2013-11-29
期刊：
影响因子：
56.9
通讯作者：
Beller, Matthias
中科院分区：
文献类型：
--
作者：
Jagadeesh, Rajenahally V.;Surkus, Annette-Enrica;Beller, Matthias
苯胺是精细化学品、农用化学品和制药工业的关键中间体，其生产依赖于贵金属催化剂，该催化剂在其他易还原官能团存在下选择性地取代芳基硝基。在这里，我们报告方便和稳定的氧化铁（Fe 2 O3）为基础的催化剂作为一个更地球丰富的替代这种转变。铁-邻菲咯啉配合物在碳上的热解形成了一种独特的结构，其中活性Fe 2 O3颗粒被氮掺杂的碳层包围。在工业上可行的条件下，许多结构不同的硝基芳烃（80多个实例）的高选择性氢化以良好至优异的产率进行。
Production of anilines-key intermediates for the fine chemical, agrochemical, and pharmaceutical industries-relies on precious metal catalysts that selectively hydrogenate aryl nitro groups in the presence of other easily reducible functionalities. Herein, we report convenient and stable iron oxide (Fe2O3)-based catalysts as a more earth-abundant alternative for this transformation. Pyrolysis of iron-phenanthroline complexes on carbon furnishes a unique structure in which the active Fe2O3 particles are surrounded by a nitrogen-doped carbon layer. Highly selective hydrogenation of numerous structurally diverse nitroarenes (more than 80 examples) proceeded in good to excellent yield under industrially viable conditions.