Sepsis Resuscitation Fluid Choice and Dose
Sepsis Resuscitation Fluid Choice and Dose
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DOI：
10.1016/j.ccm.2016.01.007
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发表时间：
2016-06-01
影响因子：
5.7
通讯作者：
Rice, Todd W.
中科院分区：
文献类型：
--
作者：
Semler, Matthew W.;Rice, Todd W.
脓毒症是一种常见的和危及生命的炎症反应，严重感染治疗抗生素和液体复苏。尽管静脉输液在脓毒症治疗中起着重要作用，但关于何种输液和输液量的基本问题仍然没有答案。在理解液体管理的生理反应方面的最新进展，以及检查复苏策略、复苏后液体平衡、胶体溶液与晶体溶液以及高氯晶体与低氯晶体的大型临床研究，为当前脓毒症液体管理方法提供了信息，并为未来的研究提出了建议。
Sepsis is a common and life-threatening inflammatory response to severe infection treated with antibiotics and fluid resuscitation. Despite the central role of intravenous fluid in sepsis management, fundamental questions regarding which fluid and in what amount remain unanswered. Recent advances in understanding the physiologic response to fluid administration, and large clinical studies examining resuscitation strategies, fluid balance after resuscitation, colloid versus crystalloid solutions, and high-versus low-chloride crystalloids, inform the current approach to sepsis fluid management and suggest areas for future research.