The Mighty Mouse: the impact of rodents on advances in biomedical research.

The Mighty Mouse: the impact of rodents on advances in biomedical research.
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发表时间:
2013-05
期刊:
Missouri medicine
影响因子:
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通讯作者:
E. Bryda
E. Bryda
中科院分区:
其他
文献类型:
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作者:
E. Bryda

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由于小鼠和大鼠在解剖学、生理学和遗传方面与人类相似,长期以来一直是生物医学研究动物模型的首选物种。啮齿动物的优点包括体型小、易于饲养、生命周期短、遗传资源丰富。大鼠资源和研究中心 (RRRC) 和 MU 突变小鼠区域资源中心 (MMRRC) 作为集中存储库,用于保存和分发数量不断增加的啮齿动物模型。
Mice and rats have long served as the preferred species for biomedical research animal models due to their anatomical, physiological, and genetic similarity to humans. Advantages of rodents include their small size, ease of maintenance, short life cycle, and abundant genetic resources. The Rat Resource and Research Center (RRRC) and the MU Mutant Mouse Regional Resource Center (MMRRC) serve as centralized repositories for the preservation and distribution of the ever increasing number of rodent models.