Temporal associations between physical illnesses and mental disorders-Results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
Temporal associations between physical illnesses and mental disorders-Results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
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DOI：
10.1016/j.comppsych.2012.12.020
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发表时间：
2013-08-01
影响因子：
7.3
通讯作者：
Grant, Bridget F.
中科院分区：
文献类型：
--
作者：
Chou, S. Patricia;Huang, Boji;Grant, Bridget F.
临床和流行病学证据已经证明了医学疾病和精神疾病之间的重要联系。然而，广泛的研究集中在医疗条件和抑郁症的共病，大多数是横断面的，集中在临床样本，并根据DSM-III或DSM-III-R诊断标准。目前的前瞻性调查研究了基线医疗条件和3年随访期间精神疾病事件之间的关联，总体而言，DSM-IV物质使用、情绪和焦虑障碍的3年发病率范围为0.65%（双相II型）至5.2%（酒精滥用）。进行多元回归分析，以检查前瞻性的身心协会，同时控制社会人口学特征，心理压力和健康相关的危险因素，和共病的身体和精神disorders.The本研究代表，据我们所知，最大的人口为基础的前瞻性研究检查的身心协会。我们的研究结果表明，药物使用，情绪和焦虑障碍的医疗疾病的共病模式明显不同。胃溃疡/胃炎、高血压和关节炎是精神疾病事件的重要预测因素。
Clinical and epidemiologic evidence has documented the significant associations between medical illnesses and psychiatric disorders. However, extensive research has focused on the comorbidity of medical conditions and depression, and most were cross sectional, focused on clinical samples, and grounded in DSM-III or DSM-III-R diagnostic criteria.The current prospective investigation examined associations among medical conditions at baseline and incident psychiatric disorders over a 3-year follow-up, using data from Waves 1 and 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).Overall, the 3-year incidence rates of DSM-IV substance use, mood and anxiety disorders ranged from 0.65% (bipolar II) to 5.2% (alcohol abuse). Multiple regression analysis was conducted to examine the prospective physical-mental associations, while controlling for sociodemographic characteristics, psychological stress and health-related risk factors, and comorbid physical and psychiatric disorders.The present study represents, to our knowledge the largest population-based prospective study examining the physical mental associations. Our results showed distinctly different patterns of comorbidity of medical illnesses with substance use, mood, and anxiety disorders. Stomach ulcer/gastritis, hypertension and arthritis emerged to be significant predictors of incident psychiatric disorders.