Fluid Movement in Occluded Single Capillaries of Rabbit Omentum
Fluid Movement in Occluded Single Capillaries of Rabbit Omentum
复制标题
兔大网膜闭塞单毛细血管的流体运动
DOI：
10.1161/01.res.28.3.358
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发表时间：
1971
影响因子：
20.1
通讯作者：
B. Zweifach
中科院分区：
文献类型：
--
作者：
J. S. Lee;L. Smaje;B. Zweifach
在Starling假说的理论基础上研究了单个毛细血管微闭塞期间跨毛细血管流体运动的顺序。对于大多数研究的毛细血管来说，该理论与使用红细胞作为液体运动标签的实验相当吻合。通过分析一次闭塞中红细胞的运动顺序，可以计算过滤系数和有效压力。有效压力范围为 28 至 38 cm H2O。由于毛细血管中的动脉压约为 20 至 30 cm H2O，因此计算表明，约 10 cm H2O 的有效压力是由组织因素贡献的，即组织空间中的负静水压或显着的胶体渗透压或两者兼而有之。计算得出的毛细管过滤系数范围为 0.01 至 0.07 μ3/(sec μ2 cm H2O)。
The sequence of transcapillary fluid movement during microocclusion of single capillaries was investigated on the theoretical basis of the Starling hypothesis. For most capillaries studied, the theory agrees reasonably well with the experiments with red cells used as the tags for fluid movement. By analyzing the sequence of the movement of the red cell in one single occlusion, it was possible to calculate the filtration coefficient and the effective pressure. The effective pressure ranged from 28 to 38 cm H2O. Since the arterial pressure in the capillary is about 20 to 30 cm H2O, the calculations suggest that about 10 cm H2O of the effective pressure is contributed by tissue factors, i.e., a negative hydrostatic pressure or a substantial colloidal osmotic pressure in the tissue space or both. The calculated filtration coefficient for the capillaries ranged from 0.01 to 0.07 μ3/(sec μ2 cm H2O).