POLYMERIC CALCIUM-PHOSPHATE CEMENTS - ANALYSIS OF REACTION-PRODUCTS AND PROPERTIES
POLYMERIC CALCIUM-PHOSPHATE CEMENTS - ANALYSIS OF REACTION-PRODUCTS AND PROPERTIES
复制标题
DOI：
10.1016/0109-5641(93)90104-x
复制
发表时间：
1993-01-01
期刊：
影响因子：
5
通讯作者：
CHOW, LC
中科院分区：
文献类型：
--
作者：
MIYAZAKI, K;HORIBE, T;CHOW, LC
研究了水基聚合磷酸钙骨水泥（PCPC）的化学和力学性能。这些水泥是通过混合几种类型的水溶性聚合物得到的，明胶、聚（乙烯醇）（PVA）和聚（烯酸）如聚（丙烯酸），与由等摩尔量的磷酸四钙（TTCP）和无水磷酸二钙（DCPA）组成的磷酸钙粘固剂（CPC）混合物以及几种其它含TTCP的混合物。所有PCPC均观察到骨水泥形成。使用明胶和PVA骨水泥，在24小时内观察到大量羟基磷灰石（HA）形成。它们的凝固时间和机械性能与纯无机CPC相似，纯无机CPC是由TTCP和DCPA在水中反应得到的。虽然明胶-CPC水泥的机械性能仅略有改善，但其处理特性上级CPC。使用聚羧酸聚合物与CPC获得了显著更快的凝固和更强的水泥。然而，在这些类型的聚合物骨水泥中，即使在37 ℃的蒸馏水中储存1个月后，也仅观察到少量的HA。本研究证明了基于水溶性聚合物与自固化磷酸钙粉末混合物的相互作用制备几种新型牙科粘固剂的可行性。
Chemical and mechanical properties of water-based polymeric calcium phosphate cements (PCPC) were investigated. These cements were derived from mixing several types of water-soluble polymers, e.g., gelatin, poly(vinyl alcohol) (PVA), and poly(alkenoic acids) such as poly(acrylic acid), with a calcium phosphate cement (CPC) mixture consisting of equimolar amounts of tetracalcium phosphate (TTCP) and anhydrous dicalcium phosphate (DCPA) as well as several other TTCP-containing mixtures. Cement formation was observed with all of the PCPCs. With the gelatin and PVA cements, significant amounts of hydroxyapatite (HA) formation were observed within 24h. Their setting times and mechanical properties were similar to those of the purely inorganic CPC that is derived from the reaction of TTCP and DCPA in water. Although the mechanical properties of a gelatin-CPC cement were only slightly improved, its handling characteristics were superior to that of CPC. Significantly faster setting and stronger cements were obtained using polycarboxylic acid polymers with CPC. However, only small amounts of HA were observed in these types of polymeric cements even after 1 mon storage in distilled water at 37-degrees-C. This research demonstrates the feasibility of preparing several new types of dental cements based on the interaction of water-soluble polymers with a self-setting calcium phosphate powder mixture.