Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration.
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration.
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DOI：
10.1186/1741-7015-10-51
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发表时间：
2012-05-29
期刊：
影响因子：
9.3
通讯作者：
Taube SE
中科院分区：
文献类型：
--
作者：
Altman DG;McShane LM;Sauerbrei W;Taube SE
肿瘤标志物预后研究报告建议（REMARK）清单包括20项已发表的肿瘤标志物预后研究报告。它是为了解决在报告这类研究方面普遍存在的缺陷而制定的。在本文中，我们扩展了REMARK清单，通过更好地理解每个项目的意图以及为什么这些信息对报告很重要，来提高其使用和有效性。备注建议包括研究目标和假设、受试者选择、标本和测定考虑因素、标志物测量方法、统计设计和分析以及研究结果的透明和完整描述。对清单中的每一项都作了解释，并附有已公布的良好报告实例和报告质量的相关经验证据。我们突出讨论“REMARK profile”，这是一种用于总结关键研究细节的建议表格格式。本文提供了一个全面的概述，以教育良好的报告，并提供了一个有价值的参考，为许多问题时，考虑设计，进行和分析肿瘤标志物研究和预后研究在医学一般。为了鼓励肿瘤标志物预后研究的报告建议（REMARK）的传播：解释和评价，这篇文章也发表在PLoS Medicine上。
The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) checklist consists of 20 items to report for published tumor marker prognostic studies. It was developed to address widespread deficiencies in the reporting of such studies. In this paper we expand on the REMARK checklist to enhance its use and effectiveness through better understanding of the intent of each item and why the information is important to report. REMARK recommends including a transparent and full description of research goals and hypotheses, subject selection, specimen and assay considerations, marker measurement methods, statistical design and analysis, and study results. Each checklist item is explained and accompanied by published examples of good reporting, and relevant empirical evidence of the quality of reporting. We give prominence to discussion of the 'REMARK profile', a suggested tabular format for summarizing key study details. The paper provides a comprehensive overview to educate on good reporting and provide a valuable reference for the many issues to consider when designing, conducting, and analyzing tumor marker studies and prognostic studies in medicine in general. To encourage dissemination of the Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration, this article has also been published in PLoS Medicine.
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影响因子：
2
作者：
Beyersmann, Jan;Wolkewitz, Martin;Schumacher, Martin
通讯作者：
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2
作者：
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影响因子：
3.3
作者：
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DOI：
10.1016/s0360-3016(00)01507-8
发表时间：
2001-02-01
影响因子：
7
作者：
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通讯作者：
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影响因子：
8.8
作者：
Altman, D G;De Stavola, B L;Love, S B;Stepniewska, K A
通讯作者：
Stepniewska, K A