COLUMNAR ORGANIZATION OF DIRECTIONALLY SELECTIVE CELLS IN VISUAL AREA MT OF THE MACAQUE
COLUMNAR ORGANIZATION OF DIRECTIONALLY SELECTIVE CELLS IN VISUAL AREA MT OF THE MACAQUE
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DOI：
10.1152/jn.1984.51.1.16
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发表时间：
1984-01-01
影响因子：
2.5
通讯作者：
GROSS, CG
中科院分区：
文献类型：
--
作者：
ALBRIGHT, TD;DESIMONE, R;GROSS, CG
本文对猕猴视区MT区的单个神经元进行了研究，以探讨其定向选择性细胞的空间分布。动物被麻醉，并用一氧化二氮麻醉。所有MT神经元(n=614)对运动刺激的反应均好于对静止刺激的反应。对于55%的神经元来说，对运动刺激的反应与刺激的颜色、形状、长度或方向无关。对于剩余的细胞，刺激长度影响响应幅度和调谐带宽，但不影响首选方向。根据MT神经元对运动刺激的敏感性将其分为4类：60%对1个运动方向反应最好，24%对1个运动方向反应较弱，8%对2个相反运动方向反应良好，8%对所有运动方向反应相同。穿透上连续采样单元的方向首选项以小增量更改，或偶尔以.apprx更改。180.度.运动方向有一个系统的表示法。运动轴的表示，即刺激沿其移动的路径的方向，比运动方向的表示更连续。穿透角与运动偏好轴的变化率之间存在系统的关系，表明运动偏好轴相似的细胞呈垂直柱排列。在MT地区，运动轴柱似乎以连续板条的形式存在。这些平板的大小是180度。运动轴的大小表示为400-500微米的皮质。穿透角与180°频率之间也存在着系统的关系。反转，表示具有相似运动方向偏好的单元格也被组织在垂直列中，而具有相反方向偏好的单元格位于单个运动轴列内的相邻列中。就像在猕猴的纹状皮质中一样。500µm的皮质含有局部分析刺激定向的机制，因此在MT.apprx。500µm的皮质包含用于局部分析刺激运动的机制。
Single neurons in visual area MT of the macaque were studied in order to examine the spatial distribution of its directionally selective cells. The animals were paralyzed and anesthetized with nitrous oxide. All MT neurons (n = 614) responded better to moving stimuli than to stationary stimuli. For 55% of the neurons, responses to moving stimuli were independent of stimulus color, shape, length, or orientation. For the remaining cells, stimulus length affected the response magnitude and tuning bandwidth but not the preferred direction. MT neurons were divided into 4 categories on the basis of their sensitivity to moving stimuli: 60% responded best to 1 direction of motion, 24% responded best to 1 direction with a weaker response in the opposite direction, 8% responded equally well to 2 opposite directions of motion, and 8% responded equally well to all directions of motion. The direction preferences of successively sampled cells on a penetration either changed by small increments or occasionally by .apprx. 180.degree.. There is a systematic representation of direction of motion. The representation of axis of motion, i.e., the orientation of the path along which a stimulus moves, is more continuous than the representation of direction of motion. There was a systematic relationship between penetration angle and rate of change of preferred axis of motion, indicating that cells with a similar axis of motion preference are arranged in vertical columns. Axis of motion columns appear to exist in the form of continuous slabs in area MT. The size of these slabs is such that 180.degree. of axis of motion are represented in 400-500 .mu.m of cortex. There was also a systematic relationship between penetration angle and frequency of 180.degree. reversals, indicating that cells with a similar direction of motion preference are also organized in vertical columns and cells with opposite direction preferences are located in adjacent columns within a single axis of motion column. Just as in macaque striate cortex where .apprx. 500 .mu.m of cortex contain the mechanism for the local analysis of stimulus orientation, so in MT .apprx. 500 .mu.m of cortex contain the mechanism for the local analysis of stimulus motion.