Regulatory roles of three miRNAs on allergen mRNA expression in Tyrophagus putrescentiae
Regulatory roles of three miRNAs on allergen mRNA expression in Tyrophagus putrescentiae
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DOI：
10.1111/all.15111
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发表时间：
2021-09
期刊：
影响因子：
12.4
通讯作者：
Ying Zhou;Qingqing Li;Ruilin Pan;Qiong Wang;Xuming Zhu;C. Yuan;Fangfang Cai;Yadong Gao
中科院分区：
文献类型：
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作者：
Ying Zhou;Qingqing Li;Ruilin Pan;Qiong Wang;Xuming Zhu;C. Yuan;Fangfang Cai;Yadong Gao
腐食酪螨是城乡环境中的重要螨种，可引起致敏和过敏性疾病。虽然有证据表明microRNAs（miRNAs）可以调节过敏原编码基因的表达，但没有研究直接研究这种可能性。在这里，这一差距是通过分析miRNA和阐明其目标过敏原信使RNA（mRNA）在这个螨种解决。
Tyrophagus putresecentiae is an important mite species in rural and urban environments, causing sensitization and allergic disease. While evidence suggests that microRNAs (miRNAs) may regulate the expression of allergen‐encoding genes, no study has directly investigated this possibility. Here, this gap was addressed by profiling miRNAs and elucidating their target allergen messenger RNAs (mRNAs) in this mite species.