Beyond licensing and disarming: A quantitative view on NK-cell education
Beyond licensing and disarming: A quantitative view on NK-cell education
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DOI：
10.1002/eji.200838760
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发表时间：
2008-11-01
影响因子：
5.4
通讯作者：
Hoglund, Petter
中科院分区：
文献类型：
--
作者：
Brodin, Petter;Hoglund, Petter
在这篇文章中，我们将超越目前对NK细胞教育不同模型的争议，而是讨论表征MHC I类指导NK细胞功能发育的特性。我们认为，这种发展，代表了NK细胞教育的终点，是一个定量和动态的，甚至可能是可逆的过程。
In this article, we will move beyond the current controversy of different models for NK-cell education and instead discuss the properties characterizing MHC class I-guided functional development of NK cells. We will argue that this development, which represents the endpoint of NK-cell education, is a quantitative and dynamic, and perhaps even reversible, process.