Motility-mediated regulation of virulence in Pseudomonas syringae
Motility-mediated regulation of virulence in Pseudomonas syringae
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DOI：
10.1016/j.pmpp.2016.02.005
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发表时间：
2016-07-01
影响因子：
2.7
通讯作者：
Taguchi, Fumiko
中科院分区：
文献类型：
--
作者：
Ichinose, Yuki;Sawada, Takahiro;Taguchi, Fumiko
我们对紫丁香假单胞菌进行了调查。利用大量与毒力相关的突变体进行烟粉与植物的相互作用。鞭毛蛋白缺陷突变体Delta flic失去了鞭毛运动和产生N-酰基高丝氨酸内酯的能力；它引起疾病症状的能力降低，但编码多药外排泵转运蛋白mexEFoprN的基因表达被激活。一个IV型菌毛(T4P)缺陷突变体Delta Pila失去了群体运动能力，降低了HRP相关基因的表达，降低了对寄主烟草的毒力，但编码另一种多药外排泵转运蛋白mexABoprM的基因表达被激活。这些结果表明，调控鞭毛和T4P介导的运动的基因也调节其他毒力相关基因的表达。(C)2016爱思唯尔有限公司。保留所有权利。
We have investigated Pseudomonas syringae pv. tabaci-plant interactions using a large variety of virulence-related mutants. A flagellin-defective mutant, Delta fliC, lost flagellar motility and the ability to produce N-acyl homoserine lactones; it had reduced ability to cause disease symptoms, but the expression of genes encoding a multidrug efflux pump transporter, mexEFoprN, was activated. A type IV pili (T4P)-defective mutant, Delta pilA, lost swarming motility, had reduced expression of hrp-related genes and virulence toward the host tobacco plant, but expression of the genes encoding another multidrug efflux pump transporter, mexABoprM, was activated. These results suggest that the genes regulating flagella- and T4P-mediated motilities also regulate expression of other virulence-related genes. (C) 2016 Elsevier Ltd. All rights reserved.