Perception of emotional speech in Parkinson's disease
Perception of emotional speech in Parkinson's disease
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DOI：
10.1002/mds.21038
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发表时间：
2006-01-01
影响因子：
8.6
通讯作者：
Dengler, Reinhard
中科院分区：
文献类型：
--
作者：
Schroeder, Christine;Moebes, Janine;Dengler, Reinhard
帕金森病（PD）的非运动症状涉及认知和情感逐渐受到关注。本研究的目的是调查与健康对照组（HC，n = 14）相比，PD患者（n = 14）的情绪韵律识别。在被动听和主动目标检测指令下，采用改良的oddball范式记录事件相关脑电位（ERP）。结果表明，PD患者在分类情感韵律方面的表现较差。情绪偏差（快乐/悲伤）在被动听力过程中产生的ERP显示幅度减少的失配相关的负性悲伤偏差，表明PD的情绪韵律的早期前注意处理的损害。(C)2006年，《社会运动》创刊。
Nonmotor symptoms in Parkinson's disease (PD) involving cognition and emotionality have progressively received attention. The objective of the present study was to investigate recognition of emotional prosody in patients with PD (n = 14) in comparison to healthy control subjects (HC, n = 14). Event-related brain potentials (ERP) were recorded in a modified oddball paradigm under passive listening and active target detection instructions. Results showed a poorer performance of PD patients in classifying emotional prosody. ERP generated by emotional deviants (happy/sad) during passive listening revealed diminished amplitudes of the mismatch-related negativity for sad deviants, indicating an impairment of early preattentive processing of emotional prosody in PD. (C) 2006 Movement Disorder Society.