DEPRESSION IN EPILEPSY - SIGNIFICANCE AND PHENOMENOLOGY
DEPRESSION IN EPILEPSY - SIGNIFICANCE AND PHENOMENOLOGY
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DOI：
10.1001/archneur.1986.00520080014012
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发表时间：
1986-08-01
影响因子：
--
通讯作者：
BENSON, DF
中科院分区：
文献类型：
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作者：
MENDEZ, MF;CUMMINGS, JL;BENSON, DF
抑郁症在癫痫患者中很常见，但关于这种关系的研究很少。我们调查了同等残疾门诊患者的抑郁症患病率及其在精神病院住院患者中的现象学。 175 名门诊癫痫患者中的 55% 和 70 名匹配对照者中的 30% 报告患有抑郁症； 30% 的癫痫患者和 7% 的对照者报告称在经期有自杀企图。癫痫患者因抑郁症住院的可能性是非癫痫患者的四倍。二十名抑郁性癫痫住院患者的特征是“内源性”而非“神经质”特征，具有更多精神病特征、偏执和潜在的慢性心境恶劣。 16 名患者患有复杂部分性癫痫发作，11 名患者中有 10 名患者的脑电图焦点偏向左半球。这些结果表明由于边缘功能障碍而导致特定的癫痫精神综合征。
Depression is common in epileptics, but few studies of this relationship exist. We investigated the prevalence of depression in comparably disabled outpatients and its phenomenology in psychiatrically hospitalized inpatients. Fifty-five percent of 175 outpatient epileptics and 30% of 70 matched controls reported depression; 30% of epileptics vs 7% of controls reported period suicide attempts. Epileptics were four times more likely to have been hospitalized for depression than nonepileptics. Twenty depressed epileptic inpatients were characterized by "endogenous" rather than "neurotic" features with more psychotic traits, paranoia, and underlying chronic dysthymia. Sixteen patients had complex partial seizures, and ten of 11 patients had a lateralized electroencephalographic focus lateralized to the left hemisphere. These results suggest a specific epileptic psychosyndrome due to limbic dysfunction.