GENERAL-PRACTITIONERS AWARENESS OF COLORECTAL-CANCER - A 10 YEAR REVIEW
GENERAL-PRACTITIONERS AWARENESS OF COLORECTAL-CANCER - A 10 YEAR REVIEW
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DOI：
10.1136/bmj.301.6744.152
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发表时间：
1990-07-21
影响因子：
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通讯作者：
CHEETHAM, NM
中科院分区：
文献类型：
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作者：
DIXON, AR;THORNTONHOLMES, J;CHEETHAM, NM
丙胺卡因-木质素乳膏（Emla（局部麻醉剂的低共熔混合物），Astra Pharmaceuticals）在减轻儿童静脉穿刺和其他小型皮肤手术疼痛方面的疗效已得到充分证实。它特别适用于需要反复皮肤穿刺的患者。该制剂在油性基质中含有丙胺卡因25 g/l和木质素25 g/l。丙胺卡因与高铁血红蛋白血症有关，其两种代谢产物4-羟基-2-甲基苯胺和2-甲基苯胺（邻甲苯胺）与该疾病有关。
The efficacy of prilocaine-lignocaine cream (Emla (eutectic mixture of local anaesthetics), Astra Pharmaceuticals) in reducing the pain of venepuncture and other minor skin procedures in children is well estab-lished. It is particularly useful in patients who require repeated skin puncture.'The preparation contains prilocaine 25 g/l and lignocaine 25 g/l in an oily base. Prilocaine is associated with methaemoglobinaemia, two of its metabolites, 4-hydroxy-2-methylaniline and 2-methylaniline (o-toluidine), having been implicated in this condition.