Change in the number of patients after the adoption of IADPSG criteria for hyperglycemia during pregnancy in Japanese women
Change in the number of patients after the adoption of IADPSG criteria for hyperglycemia during pregnancy in Japanese women
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DOI：
10.1016/j.diabres.2010.08.023
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发表时间：
2010-12-01
影响因子：
5.1
通讯作者：
Minakami, Hisanori
中科院分区：
文献类型：
--
作者：
Morikawa, Mamoru;Yamada, Takashi;Minakami, Hisanori
目的：为了评估日本孕妇与高血糖症的变化后，通过IADPSG.Methods提出的标准：研究对象包括228名日本妇女的血糖水平>= 7.8 mmol/L的葡萄糖激发试验，随后进行了葡萄糖耐量试验的1038名妇女单胎妊娠。在日本，妊娠期糖尿病（GDM）的诊断目前采用JSOG标准。在228名妇女中，根据JSOG标准，所有25名患有GDM的妇女和另外43名没有GDM的妇女根据IADPSG标准被归类为患有高血糖症，导致高血糖患者从2.4%（25/1038）增加至6.6%（68/1038）。43名新诊断GDM的妇女中出生体重≥ 3600 g的婴儿数量明显多于160名血糖正常的妇女（14% [6/43] vs. 3.8% [6/160]，p = 0.02）。新诊断GDM.Conclusion：IADPSG标准增加了至少2.7倍的患者数量，但可能是具有成本效益的减少巨大儿方面的一个婴儿的出生体重>= 3600 g的减少，需要治疗的患者人数至少为9.8。(C)2010爱思唯尔爱尔兰有限公司版权所有。
Aims: To assess how the number of Japanese pregnant women with hyperglycemia changes after the adoption of the criteria proposed by the IADPSG.Methods: The study subjects comprised 228 Japanese women with a plasma glucose level >= 7.8 mmol/L on a glucose challenge test and who subsequently underwent a glucose tolerance test among 1038 women with singleton pregnancies. Gestational diabetes mellitus (GDM) is currently diagnosed using the JSOG criteria in Japan.Results: Of the 228 women, all 25 women with GDM and an additional 43 women without GDM according to the JSOG criteria were classified as having hyperglycemia according to the IADPSG criteria, resulting in an increase of patients with hyperglycemia from 2.4% (25/1038) to 6.6% (68/1038). The number of infants with a birthweight >= 3600 g was significantly larger among the 43 women with newly diagnosed GDM than among the 160 women who remained normoglycemic (14% [6/43] vs. 3.8% [6/160], p = 0.02). The calculated number of patients requiring treatment for a reduction of one infant with a birthweight >= 3600 g was at least 9.8 for women with newly diagnosed GDM.Conclusion: The IADPSG criteria increase the number of patients by at least 2.7-fold but may be cost-effective with respect to the resulting reduction in macrosomia. (C) 2010 Elsevier Ireland Ltd. All rights reserved.