Reproducibility of dual-energy X-ray absorptiometry measurements in prepubertal girls.
Reproducibility of dual-energy X-ray absorptiometry measurements in prepubertal girls.
复制标题
青春期前女孩双能 X 射线吸收测量的重现性。
DOI：
10.1002/j.1550-8528.1998.tb00348.x
复制
发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Weinsier,RL
中科院分区：
文献类型：
--
作者：
Figueroa-Colon,R;Mayo,MS;Treuth,MS;Aldridge,RA;Weinsier,RL
目的：生长和发育的调节、临床评估和肥胖是营养相关研究的领域，其中准确评估身体组成是重要的。我们想验证双能X线吸收法（DXA）测量在健康女孩中可重复的假设。研究方法和程序：我们使用DXA测量了健康青春期前女孩的全身成分，两次间隔6周。结果：我们研究了61名健康、体重正常的青春期前女孩，年龄为4.8岁至10.3岁。访视1和访视2之间女孩的DXA衍生平均体重显著增加（27.14 kg vs. 27.80 kg，P<0.0001）。体重增加是由于全身无脂肪质量（FFM）（19.53 kg对19.89 kg，P<0.001）、全身骨量（1.05 kg对1.07 kg，P<0.0001）和全身脂肪质量（7.61 kg对7.91 kg，P<0.03）显著增加。在第1次和第2次访视之间，女孩的DXA得出的平均躯干总质量显著增加（11.23 kg vs. 11.63 kg，p<<0.0001），腿部总质量也显著增加（9.33 kg vs. 9.53 kg，p<<0.001），尽管在手臂总质量方面没有观察到显著差异（2.52 kg vs. 2.54 kg，p< = 0.37）。DXA测量的Pearson相关系数（r）和总变异系数（CV）分别为：体重-r = 0.99，CV= 1.97%，全身FFM-r = 0.96，CV = 2.30%，全身骨量-r = 0.99，CV = 2.08%，全身脂肪量-r = 0.96，CV = 6.55%;总体脂百分比-r = 0.91，CV = 5.69%;总躯干质量-r = 0.96，CV = 3.59%;总手臂质量-r = 0.95，CV = 4.09%;总腿部质量-r = 0.99，CV = 2.75%。讨论：全身FFM、全身骨量、全身脂肪量、全身脂肪量百分比以及DXA区域质量测定在健康、正常体重、青春期前女孩中具有高度重现性。我们强烈建议使用DXA对5岁至10岁的女孩进行全身成分研究。
Objective: Regulation of growth and development, clinical assessment, and obesity are among the areas of nutritionrelated research, wherein accurate assessment of body composition is important. We want to test the hypothesis that dual‐energy X‐ray absorptiometry (DXA) measurements are reproducible in healthy girls.Research Methods and Procedures: We determined total body composition measurements in healthy prepubertal girls using DXA twice, 6 weeks apart.Results: We studied 61 healthy, normal‐weight, prepubertal girls, aged 4.8 years to 10.3 years. The girls' DXA‐derived mean weight between visits 1 and 2 significantly increased (27.14 kg vs. 27.80 kg,P<0.0001). The increased weight was due to significant increases in total body fat‐free mass (FFM) (19.53 kg vs. 19.89 kg,P<O.001), total body bone mass (1.05 kg vs. 1.07 kg,P<0.0001), and total body fat mass (7.61 kg vs. 7.91 kg,P<0.03). The girls' DXA‐derived mean total trunk mass between visits 1 and 2 significantly increased (11.23 kg vs. 11.63 kg,p<<0.0001), as did total leg mass (9.33 kg vs. 9.53 kg,p<<0.001), although no significant differences were observed in total arm mass (2.52 kg vs. 2.54 kg,p< = 0.37). The Pearson coefficient of correlation (r) and total coefficient of variation (CV) for intraindividual measurements by DXA were: weight—r= 0.99, CV= 1.97%; total body FFM—r= 0.96, CV = 2.30%; total body bone mass—r= 0.99, CV = 2.08%; total body fat mass—r= 0.96, CV = 6.55%; percentage total body fat—r= 0.91, CV = 5.69%; total trunk mass—r= 0.96, CV = 3.59%; total arm mass—r= 0.95, CV = 4.09%; and total leg mass—r= 0.99, CV = 2.75%.Discussion: Total body FFM, total body bone mass, total body fat mass, percentage of total body fat mass, as well as regional mass determinations by DXA, were highly reproducible in healthy, normal‐weight, prepubertal girls. We highly recommend the use of DXA for total body composition studies in girls aged 5 years to 10 years.