Thickness of the retinal nerve fiber layer in patients with anisometropic and strabismic amblyopia.
Thickness of the retinal nerve fiber layer in patients with anisometropic and strabismic amblyopia.
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DOI：
10.1076/stra.11.1.1.14091
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发表时间：
2003-03-01
期刊：
影响因子：
0.9
通讯作者：
Karaagaoglu, Ergun
中科院分区：
文献类型：
--
作者：
Bozkurt, Banu;Irkec, Murat;Karaagaoglu, Ergun
目的：比较屈光参差和斜视性弱视患者弱视眼与正常眼的视网膜神经纤维层厚度。方法：使用GDx神经纤维分析仪（NFA）进行扫描激光偏振测量，这是一种扫描激光检眼镜，基于RNFL的双折射，在体内定量客观地测量乳头周围RNFL的厚度。18名屈光参差、2名斜视和4名合并弱视（包括屈光参差和斜视）患者参加了这项研究。男9例，女15例，年龄7 ~ 66岁。采用学生t检验比较弱视眼和健全眼的14项GDx参数。结果：两组患者GDx参数差异无统计学意义[p > 0.5]。弱视组优等平均值为79.50微米，弱视组优等平均值为80.41微米，健康眼优等平均值为80.75微米，健康眼优等平均值为82.75微米。弱视眼和健全眼的平均厚度没有差异（分别为65.50微米和66.45微米）。结论：扫描激光偏振测量单侧弱视患者双眼视网膜厚度无明显差异。
PURPOSE: To compare the retinal nerve fiber layer [RNFL] thickness of the amblyopic eye with that of the normal eye in patients with anisometropic and strabismic amblyopia.METHODS: Scanning laser polarimetry was performed with the GDx Nerve Fiber Analyzer (NFA), a scanning laser ophthalmoscope that measures the thickness of the peripapillary RNFL quantitatively and objectively, in vivo, based on the birefringence of the RNFL. Eighteen anisometropic, two strabismic and four combined amblyopic (both anisometropia and strabismus) patients were enrolled in the study. There were 9 male and 15 female patients, age range 7-66 years. Using Student's t-test, 14 GDx parameters in the amblyopic eyes and sound eyes were compared.RESULTS: The GDx parameters showed no significant differences between the two groups [p > 0.5]. The superior average and inferior average values were 79.50 microm and 80.41 microm, respectively, in the amblyopic group, and 80.75 microm and 82.75 microm, respectively, in the healthy eyes. The average thickness did not differ between amblyopic and sound eyes (65.50 microm and 66.45 microm, respectively).CONCLUSION: Assessment of RNFL thickness by means of scanning laser polarimetry revealed no difference between the two eyes in patients with unilateral amblyopia.