Hodgkin's disease complicated by radiation sarcoma in bone.
Hodgkin's disease complicated by radiation sarcoma in bone.
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霍奇金病并发骨放射性肉瘤。
DOI：
10.1259/0007-1285-53-628-314
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
H. Woodard
中科院分区：
文献类型：
--
作者：
J. Smith;R. O’Connell;A. Huvos;H. Woodard
在过去的八年里，该中心共收治了七名霍奇金病患者，他们在接受治疗后在放射野患上了骨肉瘤。何杰金氏病患者放射诱导的骨肉瘤的文献很少。大量的病例似乎是一个重要的新进展，并导致我们回顾了过去40年来在该中心看到的所有放射性肉瘤（RIS）患者。在37例以前正常骨的RIS患者中，只有一名患者患有潜在的霍奇金病，他在27年前被发现。何杰金氏病和乳腺癌是最常见的原发性基础疾病，因此，肩胛骨是放射性肉瘤最常见的部位。详细讨论了8例何杰金氏病患者的临床病史和影像学表现。
Seven patients after treatment of Hodgkin's Disease who developed bone sarcomas in the radiation field were seen at this centre over the past eight years. Radiation-induced sarcoma in bone in patients with Hodgkin's Disease is poorly documented. The large number of cases appeared to be an important new development and led to our review of all the patients with radiation-induced sarcomas (RIS) seen at this centre over the past 40 years. Thirty-seven patients with RIS in previously normal bone were found, and of these, only one patient with underlying Hodgkin's Disease, who was seen here 27 years earlier. Hodgkin's Disease and breast cancer were the most common primary underlying conditions and, as a result, the bones of the shoulder girdle were the commonest site of radiation-induced sarcoma. The clinical histories and radiographic findings of the eight patients with underlying Hodgkin's Disease are discussed in detail.