Coumarin-based novel fluorescent zinc ion probe in aqueous solution

Coumarin-based novel fluorescent zinc ion probe in aqueous solution
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水溶液中基于香豆素的新型荧光锌离子探针

DOI:
10.1016/j.tet.2013.03.032
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发表时间:
2013-06-10
期刊:
影响因子:
2.1
通讯作者:
Yang, Guang-Fu
Yang, Guang-Fu
中科院分区:
化学3区
文献类型:
--
作者:
Li, Jun;Zhang, Chun-Fang;Yang, Guang-Fu

文献摘要

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A novel coumarin-derived fluorescent probe, FCP, was designed for Zn2+ quantification based on the photo-induced electron transfer (PET) mechanism. This probe selectively and sensitively detects Zn2+ in aqueous solution with wide pH range. Large fluorescence enhancement (13-fold) was observed upon the addition of Zn2+. FCP also displays excellent cell permeability in HeLa cell model and very low cytotoxicity to HEK-293 cell model. (C) 2013 Elsevier Ltd. All rights reserved.