Visual distraction: an altered aiming spatial response in dementia.
Visual distraction: an altered aiming spatial response in dementia.
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DOI：
10.1159/000338571
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发表时间：
2012-01
影响因子：
2.3
通讯作者：
Barrett AM
中科院分区：
文献类型：
--
作者：
Galletta EE;Lequerica AH;Pekrul SR;Eslinger PJ;Barrett AM
健康个体在诸如平分线等视觉空间任务中表现出左偏，这被归因于右脑优势。我们研究了这种不对称是否发生在阿尔茨海默型痴呆（pAD）患者中，这与影响颞顶区的神经退行性改变有关。在无分心、左侧视觉分心和右侧视觉分心的情况下，pAD组和对照组分别在近空间和远空间进行线平分任务。pAD患者表现出不同于对照组的运动预备“瞄准”空间偏向。在没有分心的情况下和有右侧分心的情况下，向右“瞄准”的运动故意错误都明显增加。与对照组的典型视觉运动功能相比，pAD受试者的“瞄准”运动预备脑活动可能由分心引起。
Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD) which is associated with neurodegenerative changes affecting temporoparietal regions. Subjects with pAD and matched controls performed a line bisection task in near and far space under conditions of no distraction, left-sided visual distraction and right-sided visual distraction. Participants with pAD manifested different motor-preparatory ‘aiming’ spatial bias than matched controls. There were significantly greater rightward ‘aiming’ motor-intentional errors both without distraction and with right-sided distraction. ‘Aiming’ motor-preparatory brain activity may be induced by distraction in pAD subjects as compared to typical visual-motor function in controls.