Pattern‐evoked responses and luminance‐evoked responses in the human electroretinogram.
Pattern‐evoked responses and luminance‐evoked responses in the human electroretinogram.
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人类视网膜电图中的模式诱发反应和亮度诱发反应。
DOI：
10.1113/jphysiol.1983.sp014635
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
M. Korth
中科院分区：
文献类型：
--
作者：
M. Korth
记录人眼角膜响应空间频率、亮度和对比度变化的方波条纹图案的起始和偏移的电位。在高视网膜照明（50119 明视 td）下，对图案起始的响应是正波（图案起始波），随后是负后电位。只要呈现该图案，就可以观察到稳定的正极性电位（平台电位）。对模式偏移的响应是双相负正波，随后是负后电位。通过图案起始-偏移刺激和亮度增加-减少刺激获得的波形之间的比较表明：（a）图案起始波是亮度增加和亮度减少响应之间相互作用的结果； (b) 平台电位主要是源自视网膜区域的两个受体过程的累加叠加，这些受体过程接收局部亮度的增加和减少； (c) 负-正电势是源自局部亮度增加的视网膜区域的 a 波和 b 波。图案起始波的振幅在空间频率约为 3-4 c/deg 时最大。这种行为与之前的研究人员在心理物理学上确定的对比敏感度密切相关。因此，模式起始波似乎是模式诱发反应。 b 波跟随模式偏移的幅度随着空间频率的增加而单调下降。它主要是亮度诱发的反应。在低视网膜照度（457 明视 td）下，图案起始波和图案偏移处的 b 波较小。然而，图案起始波在较低的空间频率处具有最大幅度。当空间平均亮度的增加或减少与图案开始或偏移相结合时，可以观察到图案诱发反应和亮度诱发反应之间的转变。结果表明，局部亮度的降低是引起图案相关反应的基本刺激，而局部光强度的增加会产生亮度诱发的反应。
Electrical potentials were recorded from the cornea of the human eye in response to the onset and offset of square‐wave stripe patterns varying in spatial frequency, luminance and contrast. Under high retinal illumination (50119 photopic td) the response to pattern onset was a positive wave (pattern‐onset wave) followed by a negative after‐potential. As long as the pattern was presented, a steady potential of positive polarity (plateau potential) was observed. The response to pattern offset was a biphasic negative‐positive wave followed by a negative after‐potential. A comparison between wave forms obtained with pattern onset‐offset stimuli and luminance increase‐decrease stimuli suggests: (a) the pattern‐onset wave is the result of an interaction between a luminance‐increase and a luminance‐decrease response; (b) the plateau potential is mainly an additive superposition of two receptor processes originating from retinal areas that receive increases and decreases in local luminance; (c) the negative‐positive potential is an a‐wave and a b‐wave originating from retinal areas that receive increases in local luminance. The amplitude of the pattern‐onset wave was greatest at a spatial frequency around 3‐4 c/deg. This behaviour was closely correlated with contrast sensitivity determined psychophysically by previous investigators. Therefore, the pattern‐onset wave seems to be a pattern‐evoked response. The amplitude of the b‐wave following pattern offset showed a monotonic decrease with increasing spatial frequency. It is mainly a luminance‐evoked response. Under low retinal illumination (457 photopic td) the pattern‐onset wave and the b‐wave at pattern offset were smaller. However, the pattern‐onset wave had its maximum amplitude at a lower spatial frequency. When increases or decreases in space‐average luminance were combined with pattern onset or offset, transitions between pattern‐ and luminance‐evoked responses could be observed. The results suggest that a decrease in local luminance is the essential stimulus for evoking a pattern‐related response while increases in local light intensity generate luminance‐evoked responses.