Nickel- and copper-catalyzed direct alkynylation of azoles and polyfluoroarenes with terminal alkynes under O(2) or atmospheric conditions.
Nickel- and copper-catalyzed direct alkynylation of azoles and polyfluoroarenes with terminal alkynes under O(2) or atmospheric conditions.
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DOI：
10.1021/ol100699g
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发表时间：
2010-04
期刊：
影响因子：
5.2
通讯作者：
Naoto Matsuyama;M. Kitahara;K. Hirano;T. Satoh;M. Miura
中科院分区：
文献类型：
--
作者：
Naoto Matsuyama;M. Kitahara;K. Hirano;T. Satoh;M. Miura
唑类与末端炔烃的直接C-H炔基化反应在镍/O(2)催化体系下有效进行。另一方面，铜/空气催化剂能够实现多氟芳烃与末端炔烃的偶联。这些催化剂通过正式的直接 Sonogashira 偶联提供了获得芳基乙炔的新途径。
The direct C-H alkynylation of azoles with terminal alkynes proceeds efficiently under a nickel/O(2) catalytic system. On the other hand, a copper/air catalyst enables the coupling of polyfluoroarenes with terminal alkynes. These catalyses provide new accesses to arylacetylenes through the formal direct Sonogashira coupling.