An epidemiological survey on low birth weight infants in China and analysis of outcomes of full-term low birth weight infants.
An epidemiological survey on low birth weight infants in China and analysis of outcomes of full-term low birth weight infants.
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DOI：
10.1186/1471-2393-13-242
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发表时间：
2013-12-26
影响因子：
3.1
通讯作者：
Zhang W
中科院分区：
文献类型：
--
作者：
Chen Y;Li G;Ruan Y;Zou L;Wang X;Zhang W
低出生体重（LBW）是围产期不良结局的主要原因之一，与新生儿疾病和死亡密切相关。LBW的发病率一直在上升。本研究旨在探讨中国大陆低出生体重儿的发生率、影响因素及足月低出生体重儿的围生儿结局。本文回顾性分析了2011年在中国7个地区14个省、市、自治区的39家不同类型医院出生的儿童。首先以硬拷贝形式收集数据，然后输入计算机网络数据库。共收集了112，441例病例的数据。如果数据不完整，以及妊娠24周前流产、多胎妊娠或因胎儿畸形、宫内死亡等原因引产的病例，则将其排除，共留下101，163例病例。采用SPSS18.0和SAS9.2统计软件包对收集的数据进行分析。根据这项研究，中国大陆的低出生体重发生率为6.1%，高于2000年报告的5.87%，并且不同地区的低出生体重发生率不同。三级保健医院的低出生体重发生率明显高于二级保健医院。发现LBW与母亲年龄小于20岁、母亲教育水平低、既往不良妊娠史以及妊娠合并症和并发症相关，如妊娠期高血压疾病、贫血、羊水过少、胎膜早破和妊娠糖尿病。足月低出生体重儿的死产率、新生儿重度窒息率和死亡率分别为2.42%、0.83%和3.49%。剖腹产足月低出生体重儿的死产率和新生儿死亡率分别为0.5%和1.0%，低于阴道分娩。我国低出生体重儿的发病率呈上升趋势。LBW是不良妊娠结局的主要原因。加强孕期保健和对低出生体重高危因素的管理，可降低低出生体重儿的发生率和死亡率。
Low birth weight (LBW) is one of the leading causes of adverse perinatal outcomes and is closely related to neonatal disease and death. The incidence of LBW has been increasing. The aim of this study was to investigate the current incidence rate and factors affecting low birth weight infants and perinatal outcomes of full-term low birth weight infants in mainland China. This paper describes a retrospective analysis of children born in 39 hospitals of different types in 14 different provinces, municipalities, and autonomous regions in seven districts within China throughout 2011. The data were first collected in hardcopy format and then entered into computer network databases. Data covering a total of 112,441 cases were collected. Cases were excluded if data were incomplete and in the case of miscarriage before 24 weeks of gestation, multiple pregnancies, or induction of labor due to fetal malformation, intrauterine death, and other reasons, leaving a total of 101,163 cases. SPSS 18.0 and SAS 9.2 statistical packages were used to analyze the collected data. According to this research, the incidence of LBW in mainland China was 6.1%, which is higher than the 5.87% reported in 2000, and it varied across different areas. The incidence of LBW was significantly higher in tertiary care hospitals than in secondary care hospitals. LBW was found to be associated with maternal age of less than 20 years, low level of maternal education, previous histories of adverse pregnancies, and with pregnancy comorbidities and complications, such as hypertensive disorders during pregnancy, anemia, oligohydramnios, premature rupture of membranes, and gestational diabetes. The rates of stillbirths, severe neonatal asphyxia, and deaths among full-term LBW infants were 2.42%, 0.83%, and 3.49%, respectively. The rates of stillbirths and neonatal deaths among full-term LBW infants born by caesarean section were 0.5% and 1.0%, respectively, which was lower than vaginal delivery. The incidence of LBW has increased in China. LBW is a leading cause of adverse pregnancy outcomes. Health care during pregnancy and management of high-risk factors for LBW may reduce the incidence of LWB and the death rate of LBW infants.
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DOI：
10.1016/s0020-7292(11)60006-4
发表时间：
2011-11-01
影响因子：
3.8
作者：
Christensen, Dirk L.;Kapur, Anil;Bygbjerg, Ib C.
通讯作者：
Bygbjerg, Ib C.
DOI：
10.1177/1527154412442391
发表时间：
2012-02-01
期刊：
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影响因子：
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作者：
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影响因子：
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影响因子：
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