Combined Prevalence of Frailty and Mild Cognitive Impairment in a Population of Elderly Japanese People
Combined Prevalence of Frailty and Mild Cognitive Impairment in a Population of Elderly Japanese People
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DOI：
10.1016/j.jamda.2013.03.010
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发表时间：
2013-07-01
影响因子：
7.6
通讯作者：
Suzuki, Takao
中科院分区：
文献类型：
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作者：
Shimada, Hiroyuki;Makizako, Hyuma;Suzuki, Takao
目的：虚弱和轻度认知障碍 (MCI) 的预防策略对于避免老年人未来功能衰退和痴呆非常重要。本研究的目的是利用基于人群的调查来确定日本老年人虚弱和 MCI 的单一和综合患病率，并确定虚弱和 MCI 之间的关系。设计：横断面研究。背景：普通社区。参与者：总共 5104 名老年人（年龄 65 岁或以上，平均年龄 71 岁）参加了 Obu 老年人健康促进研究 (OSHPE)。测量：每个参与者都接受了详细的身体和认知测试，以评估虚弱和 MCI。我们认为虚弱表型的特征是以下 5 个领域中的 3 个或更多领域受到限制：活动能力、力量、耐力、体力活动和营养。 MCI 筛查包括标准化个人访谈、简易精神状态检查和国家老年病学和老年学中心功能评估工具 (NCGG-FAT)，其中包括 8 项任务，用于评估逻辑记忆（立即和延迟识别）、单词列表记忆（立即和延迟回忆）、注意力和执行功能（平板电脑版轨迹制作测试 A 和 B 部分）、处理速度（平板电脑版数字符号替换测试）以及 视觉空间技能（图形选择）。 结果：虚弱、MCI 以及虚弱和 MCI 组合的总体患病率分别为 11.3%、18.8% 和 2.7%。我们发现虚弱与 MCI 之间存在显着关系（根据年龄、性别和教育程度调整的比值比为 2.0（95% 置信区间 1.5-2.5）。结论：使用 OSHPE 标准，我们发现患有 MCI 的参与者多于虚弱的参与者。在我们的人群中，虚弱和 MCI 的患病率合计为 2.7%。未来的调查有必要确定该人群是否面临更高的残疾或死亡风险。版权所有 (C) 2013 - 美国医疗主任协会有限公司。
Objective: Preventive strategies for frailty and mild cognitive impairment (MCI) are important for avoiding future functional decline and dementia in older adults. The purpose of this study was to use a population-based survey to ascertain the single and combined prevalence of frailty and MCI and to identify the relationships between frailty and MCI in older Japanese adults.Design: Cross-sectional study.Setting: General community.Participants: A total of 5104 older adults (aged 65 years or older, mean age 71 years) who were enrolled in the Obu Study of Health Promotion for the Elderly (OSHPE).Measurements: Each participant underwent detailed physical and cognitive testing to assess frailty and MCI. We considered the frailty phenotype to be characterized by limitations in 3 or more of the following 5 domains: mobility, strength, endurance, physical activity, and nutrition. Screening for MCI included a standardized personal interview, the Mini-Mental State Examination, and the National Center for Geriatrics and Gerontology-Functional Assessment Tool (NCGG-FAT), which included 8 tasks used to assess logical memory (immediate and delayed recognition), word list memory (immediate and delayed recall), attention and executive function (tablet version of Trail Making Test-part A and B), processing speed (tablet version of digit symbol substitution test), and visuospatial skill (figure selection).Results: The overall prevalence of frailty, MCI, and frailty and MCI combined was 11.3%, 18.8%, and 2.7%, respectively. We found significant relationships between frailty and MCI (the odds ratio adjusted for age, sex, and education was 2.0 (95% confidence interval 1.5-2.5).Conclusions: Using the OSHPE criteria, we found more participants with MCI than with frailty. The prevalence of frailty and MCI combined was 2.7% in our population. Future investigation is necessary to determine whether this population is at increased risk for disability or mortality. Copyright (C) 2013 - American Medical Directors Association, Inc.