On the classification of simple and complex cells
On the classification of simple and complex cells
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DOI：
10.1016/s0042-6989(02)00025-1
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发表时间：
2002-04-01
期刊：
影响因子：
1.8
通讯作者：
Ringach, DL
中科院分区：
文献类型：
--
作者：
Mechler, F;Ringach, DL
他们对初级视觉皮层的开创性研究。Hubel和Wiesel描述了两类细胞的存在，他们称之为“简单”和“复杂”。最初的分类方案是基于一些线性空间求和的部分主观检验。随后，研究者采用了一种基于响应的一阶谐波振幅与平均尖峰率之比（即F-1/F-0之比）的客观分类方法，然后用漂移正弦光栅刺激神经元。这种方法在总体上是双峰分布的，并将神经元分为两类，这与Hubel和Wiesel的经典定义非常接近。本研究表明，当细胞内反应调制和平均值的分布为单峰时，一个简单的校正模型可以预测初级视觉皮层中观察到的F-1/F-0的双峰分布。因此。与一般的看法相反，F-1/F-0的双峰性并不一定意味着存在两个离散的细胞类。在回顾文献时，我们没有发现简单/复杂二分法的独立支持。这些结果表明，在初级视觉皮层中存在两个不同的神经群。以及相关的感受野组织层次模型。需要重新评估。(C) 2002 Elsevier Science Ltd.版权所有。
In their pioneering studies of primary visual cortex. Hubel and Wiesel described the existence of two classes of cells, which they termed "simple" and "complex". The original classification scheme was based on a number of partly Subjective tests of linear spatial summation. Later, investigators adopted an objective classification method based on the ratio between the amplitude of the first harmonic of the response and the mean spike rate (or the F-1/F-0 ratio), hen the neuron is stimulated with drifting sinusoidal gratings. This measure is bimodally distributed Over the population and divides neurons into two classes that correspond closely to the classical definition by Hubel and Wiesel. Here we show that a simple rectification model can predict the observed bimodal distribution of F-1/F-0 in primary visual cortex when the distributions of the intracellular response modulation and mean are unimodal. Thus. contrary to common belief, the bimodality of F-1/F-0 does not necessarily imply the existence of two discrete cell classes, Furthermore. in reviewing the literature, we find no independent Support for a simple/complex dichotomy. These results Suggest that the existence of two distinct neural populations in primary visual cortex. and the associated hierarchical model of receptive field organization. need to be re-evaluated. (C) 2002 Elsevier Science Ltd. All rights reserved.