Confocal laser feedback microscopy for in-depth imaging applications
Confocal laser feedback microscopy for in-depth imaging applications
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DOI：
10.1049/el.2017.4333
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发表时间：
2017-12
影响因子：
1.1
通讯作者：
Alireza Mowla;T. Taimre;K. Bertling;S. Wilson;A. Rakić
中科院分区：
文献类型：
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作者：
Alireza Mowla;T. Taimre;K. Bertling;S. Wilson;A. Rakić
我们提出共聚焦激光反馈显微镜用于高散射样品的深度成像。这项技术为反射模式下的显微镜提供了紧凑的结构；它基于激光反馈干涉测量，这是一种传感技术，其中激光既充当光束的发射器，也充当光束的接收器。它在850 nm处工作，为软生物组织的非侵入性和活体成像提供了理想的平台。为了探索这项技术，作者在距表面0.43毫米的琼脂凝胶样品中对直径为10-20微米的微小玻璃球体进行了显微成像。实验结果表明，一种小巧、低成本、简单的激光扫描显微镜具有可能的生物医学成像应用的可行性。
We propose confocal laser feedback microscopy for in-depth imaging of highly scattering samples. This technique provides a compact configuration for microscopy in reflectance mode; it is based on laser feedback interferometry which is a sensing technique where the laser acts as both transmitter and receiver of the beam. Operating at 850 nm, it offers an ideal platform for non-invasive and in vivo imaging of soft biological tissues. To explore the technique, the authors performed microscopic imaging of micro-glass-spheres (with diameter sizes of 10-20 mu m) deep within an agar gel sample, at depth of 0.43 mm from the surface. Experimental results show the feasibility of a compact, low-cost, and simple laser-scanning microscope with possible biomedical imaging applications.