Design and characteristics of holographic neural photo-stimulation systems
Design and characteristics of holographic neural photo-stimulation systems
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DOI：
10.1088/1741-2560/6/6/066004
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发表时间：
2009-12-01
影响因子：
4
通讯作者：
Shoham, S.
中科院分区：
文献类型：
--
作者：
Golan, L.;Reutsky, I.;Shoham, S.
计算机全息是一种新兴的用光模式刺激神经元群的技术。全息光刺激系统可以被设计为一种强大的研究工具或紧凑的神经接口医疗设备，如光学视网膜假体。我们在这里概述了主要的设计问题，包括全息器件的选择、视场、分辨率、物理尺寸、二维和三维图案的产生及其衍射效率、算法的选择和计算量。使用实验记录的离体视网膜演示了KHz帧速率全息图案刺激系统的性能和特点。
Computer-generated holography is an emerging technology for stimulation of neuronal populations with light patterns. A holographic photo-stimulation system may be designed as a powerful research tool or a compact neural interface medical device, such as an optical retinal prosthesis. We present here an overview of the main design issues including the choice of holographic device, field-of-view, resolution, physical size, generation of two-and three-dimensional patterns and their diffraction efficiency, choice of algorithms and computational effort. The performance and characteristics of a holographic pattern stimulation system with kHz frame rates are demonstrated using experimental recordings from isolated retinas.