Bacterial Meningitis after Cochlear Implantation among Children without Polyvalent Conjugate Vaccine: A Brief Report of an Iranian Cohort Study on 371 Cases
Bacterial Meningitis after Cochlear Implantation among Children without Polyvalent Conjugate Vaccine: A Brief Report of an Iranian Cohort Study on 371 Cases
复制标题
DOI：
--
复制
发表时间：
2014-04
影响因子：
2.1
通讯作者：
S. Afsharpaiman;S. Amirsalari;M. Ajalloueyan;A. Saburi
中科院分区：
文献类型：
--
作者：
S. Afsharpaiman;S. Amirsalari;M. Ajalloueyan;A. Saburi
背景：考虑到人工耳蜗术后细菌性脑膜炎(BM)的风险，建议接种多价结合疫苗。我们的目的是评估未接种多价疫苗的儿童接受者中BM后CI的流行率。方法：我们招募了从2007到2010年间接受人工耳蜗术的371名儿童。植入前后均未接种BM多价结合疫苗。我们在植入后对所有患者进行了2年的骨髓跟踪观察。结果：仅发现1例24个月大的女性BM(占患者总数的0.3%)。未感染儿童的平均年龄为36.7±23.2个月。父母文化程度不到一半以上，约65%的患者是近亲婚姻的产物。结论：我们的研究结果表明，未接受免疫的植入人工耳蜗的儿童的BM发生率并不高于常规接种的国家的患者。我们建议，尽管建议在手术前进行适当的免疫接种，但可以在不接种疫苗的情况下进行这一程序，特别是在那些在准备疫苗方面面临资金问题的发展中国家。
Background: Regarding risk of bacterial meningitis (BM) after Cochlear implantation (CI), it was suggested to receive polyvalent conjugate vaccine. We aimed to estimate the prevalence of BM post CI in child recipients who do not receive polyvalent vaccine. Methods: We enrolled 371 children who had received cochlear implants from 2007 to 2010. None of them received pre or post implantation polyvalent conjugate vaccine for BM. We followed all of them for BM for 2 years after implantation. Results: We detected only one female case of BM (0.3% of patients) with the age of 24 months. The mean age of noninfected children was 36.7 ± 23.2 months. The education level of parents was “college level or higher” in less than half of them, and about 65% of patients were products of consanguineous marriage. Conclusions: Our findings indicated that the incidence of BM was not higher in our cochlear implanted children who did not receive immunization than patients from countries in which routine vaccination is done. We suggest that although proper immunization is recommended before surgery, this procedure could be performed without vaccination, especially in developing countries that face financial problems for preparing vaccines.