Gender influences headache characteristics with increasing age in migraine patients
Gender influences headache characteristics with increasing age in migraine patients
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DOI：
10.1177/0333102414559735
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发表时间：
2015-08-01
期刊：
影响因子：
4.9
通讯作者：
Ozturk, Musa
中科院分区：
文献类型：
--
作者：
Bolay, Hayrunnisa;Ozge, Aynur;Ozturk, Musa
背景和目的偏头痛是最常见的原发性头痛疾病之一，女性发病率是男性的三倍，尤其是在育龄期。女性占优势的神经生物学基础已经部分确立。本研究旨在探讨性别对偏头痛患者头痛表现的影响。方法研究对象为来自5家不同医院三级保健头痛门诊的2082例成人患者。评估先兆偏头痛（MwA）和无先兆偏头痛（MwoA）患者头痛特征与性别的关系。对头痛持续时间、严重程度、频率及相关症状进行性别和年龄差异评估，并对两个亚组进行分析。结果女性偏头痛患者头痛发作的持续时间和强度明显延长。恶心、电话恐惧症和畏光症在女性中更为普遍。在MwoA中，女性的中位头痛持续时间也长于男性（p=0.013）
Background and aims Migraine headache is one of the most common primary headache disorders and is three times more prevalent in women than in men, especially during the reproductive ages. The neurobiological basis of the female dominance has been partly established. The present study aimed to investigate the effect of gender on the headache manifestations in migraine patients.Methods The study group consisted of 2082 adult patients from five different hospitals' tertiary care-based headache clinics. The relationship between headache characteristics and gender was evaluated in migraine with aura (MwA) and migraine without aura (MwoA). The duration, severity, frequency of headache and associated symptoms were evaluated in both genders and age-dependent variations and analyzed in two subgroups.Results Women with migraine were prone to significantly longer duration and intensity of headache attacks. Nausea, phonophobia and photophobia were more prevalent in women. Median headache duration was also longer in women than in men in MwA (p=0.013) and MwoA (p