THE ROLE OF THE NUCLEUS RETICULARIS TEGMENTI PONTIS IN LOCOMOTION - A LESION STUDY IN THE RAT
THE ROLE OF THE NUCLEUS RETICULARIS TEGMENTI PONTIS IN LOCOMOTION - A LESION STUDY IN THE RAT
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DOI：
10.1016/0361-9230(84)90166-7
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发表时间：
1984-01-01
影响因子：
3.8
通讯作者：
MOGENSON, GJ
中科院分区：
文献类型：
--
作者：
BRUDZYNSKI, SM;MOGENSON, GJ
双侧pontis网状核（NRTP）的阳极和阴极电解损伤增加了大鼠的前向运动。运动强度与NRTP损伤百分率的相关关系表明，NRTP破坏越彻底，运动强度增加越大。在身体平衡测试中，受损大鼠同时表现出低水平的饲养和跑轮活动以及一定程度的运动协调性缺乏。ntp -小脑通路的中断，而不是与前脑结构的连接，与病变引起的向前运动增加有关。
Bilateral anodal and cathodal electrolytic lesions of the nucleus reticularis tegmenti pontis (NRTP) increased forward locomotion in rats. The correlation between the magnitude of locomotion and percent of NRTP damage demonstrated that the more complete the NRTP destruction the greater the increase of locomotion. The lesioned rats exhibited at the same time low level rearing and running wheel activity as well as some lack of motor coordination during body balance tests. Disruption of NRTP-cerebellar pathways, rather than connection with forebrain structures is associated with the lesion-induced increase of forward locomotion.