Poly(vinyl alcohol) cryogel phantoms for use in ultrasound and MR imaging
Poly(vinyl alcohol) cryogel phantoms for use in ultrasound and MR imaging
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DOI：
10.1088/0031-9155/49/24/009
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发表时间：
2004-12-21
影响因子：
3.5
通讯作者：
Peters, TM
中科院分区：
文献类型：
--
作者：
Surry, KJM;Austin, HJB;Peters, TM
聚乙烯醇冻凝胶（PVA-C）是一种仿组织材料，适用于磁共振成像和超声成像。使用10重量%的聚（乙烯醇）水溶液形成PVA-C，其通过冻融过程固化。冻融循环次数影响材料的性能。用圆柱形PVA-C样品研究了其超声磁共振成像特性。声速范围为1520 ~ 1540 m·s（-1），衰减系数范围为0.075-0.28 dB（cm·MHz）（-1）。T1和T2弛豫值分别为718-1034 ms和108-175 ms。我们还介绍了这种材料在拟人大脑模型、多体积狭窄血管模型和乳腺活检模型中的应用。对于如何在体模设计和开发过程中最好地处理这种材料提出了一些建议。
Poly(vinyl alcohol) cryogel, PVA-C, is presented as a tissue-mimicking material, suitable for application in magnetic resonance (MR) imaging and ultrasound imaging. A 10% by weight poly(vinyl alcohol) in water solution was used to form PVA-C, which is solidified through a freeze-thaw process. The number of freeze-thaw cycles affects the properties of the material. The ultrasound MR Imaging characteristic were investigated using cylindrical samples of PVA-C. The speed of sound was found to range 1520 to 1540 m s(-1), and the attenuation coefficients were in the range of 0.075-0.28 dB (cm MHz)(-1). T1 and T2 relaxation values were found to be 718-1034 ms and 108-175 ms, respectively. We also present applications of this material in an anthropomorphic brain phantom, a multi-volume stenosed vessel phantom and breast biopsy phantoms. Some suggestions are made for how best to handle this material in the phantom design and development process.