Combined experimental and numerical analysis of the flow structure into the left ventricle
Combined experimental and numerical analysis of the flow structure into the left ventricle
复制标题
DOI：
10.1016/j.jbiomech.2006.09.024
复制
发表时间：
2007-01-01
影响因子：
2.4
通讯作者：
Pedrizzetti, G.
中科院分区：
文献类型：
--
作者：
Domenichini, F.;Querzoli, G.;Pedrizzetti, G.
流体动力学仅在一定程度上用于心脏病学诊断。事实上，心脏血流的几个方面及其与病理生理学的关系尚不清楚。这里通过结合数值和实验模型来研究发展到左心室的血流。前者可以进行详细的三维分析，后者可以在当前计算能力无法达到的条件下使用，例如存在湍流。三维流动动力学根据其涡流结构进行分析。该研究在其局限性范围内提供了对心室内血流结构的进一步物理理解。这最终可以支持基于流体动力学的心脏诊断指标的开发。 (C) 2006 Elsevier Ltd. 保留所有权利。
Fluid dynamics is used for diagnosis in cardiology only to a partial extent. Indeed several aspects of cardiac flows and their relation with pathophysiology are unknown. The flow that develops into the left ventricle is here studied by using a combination of numerical and experimental models. The former allows a detailed three-dimensional analysis, the latter can be used in conditions, like in presence of turbulence, that are out of reach of the current computational power. The three-dimensional flow dynamics is analyzed in terms of its vortical structure. The study, within its limitations, provides further physical understanding about the intraventricular flow structure. This could eventually support the development of cardiac diagnostic indicators based on fluid dynamics. (C) 2006 Elsevier Ltd. All rights reserved.