Prevalence of generalized anxiety disorder and its related factors among infertile patients in Iran: a cross-sectional study
Prevalence of generalized anxiety disorder and its related factors among infertile patients in Iran: a cross-sectional study
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DOI：
10.1186/s12955-018-0956-1
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发表时间：
2018-06-19
影响因子：
3.6
通讯作者：
Maroufizadeh, Saman
中科院分区：
文献类型：
--
作者：
Omani-Samani, Reza;Ghaheri, Azadeh;Maroufizadeh, Saman
背景：广泛性焦虑症（GAD）是不孕患者中最常见的焦虑症之一。本研究旨在确定广泛性焦虑症在伊朗德黑兰不孕患者中的患病率及其相关因素。方法：本横断面研究包括2017年5月至10月在伊朗德黑兰一家转诊生育中心的1146名不孕患者。GAD采用广泛性焦虑障碍-7 （GAD-7）量表进行测量。GAD和人口统计学/生育特征之间的关联使用简单和多重逻辑回归与优势比（OR）和95%置信区间（CI）进行估计。结果：GAD-7总分平均为6.61分（SD = 5.32）。使用截断值10，GAD患病率为28.3%。在校正分析中，女性（OR = 2.54, 95% CI = 1.88-3.42, P < 0.001）、低教育水平（OR = 1.45, 95% CI = 1.08-1.94, P = 0.012）、高不孕持续时间（OR = 1.05, 95% CI = 1.01-1.09, P = 0.013）和治疗失败（OR = 1.52, 95% CI = 1.13-2.04, P = 0.006）与GAD相关。结论：广泛性焦虑症在不孕症患者中患病率较高。我们的结论是，所有不孕患者都应该筛查广泛性焦虑症的症状，并根据需要进行治疗。
Background: Generalized anxiety disorder (GAD) is one of the most prevalent anxiety disorders among infertile patients. This study aimed to determine the prevalence of GAD and its associated factors among infertile patients in Tehran, Iran.Methods: This cross-sectional study included 1146 infertile patients in a referral fertility center in Tehran, Iran between May and October 2017. GAD was measured using the Generalized Anxiety Disorder-7 (GAD-7) scale. The associations between GAD and demographic/fertility characteristics were estimated using simple and multiple logistic regression with odds ratio (OR) and 95% confidence interval (CI).Results: The mean total GAD-7 score was 6.61 (SD = 5.32). Using a cut-off value of 10, the prevalence of GAD was 28.3%. In adjusted analysis, female sex (OR = 2.54, 95% CI = 1.88-3.42, P < 0.001), low educational level (OR = 1.45, 95% CI = 1.08-1.94, P = 0.012), high infertility duration (OR = 1.05, 95% CI = 1.01-1.09, P = 0.013), and treatment failure (OR = 1.52, 95% CI = 1.13-2.04, P = 0.006) were associated with GAD.Conclusions: The prevalence of GAD is relatively high in infertile patients. We conclude that all infertile patients should be screened for symptoms of GAD and treated for this disorder as need arises.