Studies on blood eosinophils. I. Patients with a transient eosinophilia.
Studies on blood eosinophils. I. Patients with a transient eosinophilia.
复制标题
血液嗜酸性粒细胞的研究。
DOI：
--
复制
发表时间：
1976
影响因子：
4.6
通讯作者：
C. Spry
中科院分区：
文献类型：
--
作者：
P. Tai;C. Spry
对6例一过性嗜酸性粒细胞增多症患者的血嗜酸性粒细胞进行了研究，以观察血嗜酸性粒细胞是否在结构或功能上与11例正常人的血嗜酸性粒细胞不同。结果发现，许多患者的嗜酸性粒细胞空泡化，有些含有比正常少的特异性颗粒。这些嗜酸性粒细胞还具有兔IgG的Fc受体。当嗜酸性粒细胞计数恢复正常时，这些异常不再被发现。这些变化的性质进行了讨论，在组织中的嗜酸性粒细胞和其他类型的吞噬细胞响应stimulae的属性。建议的机制，他们可能已经来了。结论：嗜酸性粒细胞增多症患者的血液嗜酸性粒细胞可能在功能上成熟或在血液中对未知刺激的反应中发生改变。
Studies were done on blood eosinophils from six patients with a transient eosinophilia, to see whether blood eosinophils were structurally or functionally different from blood eosinophils in eleven normal individuals. It was found that many of the patients' eosinophils were vacuolated, and some contained less specific granules than normal. These eosinophils also possessed Fc receptors for rabbit IgG. When the eosinophil counts returned to normal these abnormalities were no longer found. The nature of these alterations are discussed in relation to the properties of eosinophils in tissues and other types of phagocytic cells responding to stimulae. Suggestions are made about the mechanisms by which they could have come about. It was concluded that blood eosinophils in patients with an eosinophilia may be functionally mature or altered in response to unknown stimulae while they are in the blood.